Results 51 to 60 of about 71,608 (264)

Endovascular Therapy for Isolated Cervical Internal Carotid Artery Occlusion

Stroke: Vascular and Interventional Neurology
Background Guidelines on endovascular therapy for acute ischemic stroke do not include isolated cervical internal carotid artery (cICA) occlusions. The effect of treating these lesions remains unclear.
Katrine Falkesgaard, Jakob N. Hedegaard, Jonas Jensen, Thabele M. Leslie‐Mazwi, Rolf A. Blauenfeldt, Claus Z. Simonsen   +5 more
doaj   +1 more source

Chronic Changes In Oligodendrocyte Sub-Populations After Middle Cerebral Artery Occlusion in Neonatal Mice [PDF]

, 2023
Alexandra P. Frazier, Danae Mitchell, Katherine S. Given, Genevieve Hunn, Amelia Burch, Christine R. Childs, Myriam Moreno‐Garcia, Michael R. Corigilano, Nidia Quillinan, Wendy B. Macklin, Paco S. Herson, Andra Dingman   +11 more
openalex   +1 more source

Inhibition of SLC11A1‐Mediated Lysosomal Iron Accumulation in Microglia Promotes Repair Following White Matter Stroke

Advanced Science, EarlyView.
Genetic and pharmacological inhibition of SLC11A1 functioning as an H+/Fe2+ antiporter–mediated lysosomal iron accumulation in microglia promotes lysosomal lumen acidification, increases CTSD expression, enhances lysosomal myelin debris uptake and degradation, and promotes repair following white matter stroke. ABSTRACT White matter stroke (WMS) results
Lingling Qiu, Yajie Zhang, Yushi Tang, Hongli Hu, Ying Zhang, Junwen Xue, Hao Wang, Yecheng Wang, Chunfeng Liu, Jia Jia, Jian Cheng, Yongjun Cao   +11 more
wiley   +1 more source

Intracranial Atherosclerotic Disease-Related Acute Middle Cerebral Artery Occlusion Can Be Predicted by Diffusion-Weighted Imaging

Frontiers in Neuroscience, 2019
Background: The differentiation of large vessel occlusion caused by intracranial atherosclerotic stenosis (ICAS) or intracranial embolism significantly impacts the course of treatment (i.e., intravenous thrombolysis versus mechanical thrombectomy) for ...
Huijun Zhang, Xuan Sun, Qiong Huang, Xiangming Wang, Yunhua Yue, Mingfeng Ju, Xiaoping Wang, Ji Ding, Zhongrong Miao   +8 more
doaj   +1 more source

Carotid Thrombosis in a Crack Cocaine Smoker Woman

Case Reports in Vascular Medicine, 2020
Introduction. We report a case of stroke in a crack smoker with occlusion of the middle cerebral artery and a large thrombus in the carotid artery. Case Presentation.
Mattia Cosenza, Luigi Panza, Anna Paola Califano, Carolina Defendini, Maria D’Andria, Roberto Romiti, Antonio Fabio Massimo Vainieri, Sergio Morelli   +7 more
doaj   +1 more source

Microglial Fkbp5 Impairs Post‐Stroke Vascular Integrity and Regeneration by Promoting Yap1‐Mediated Glycolysis and Oxidative Phosphorylation

Advanced Science, EarlyView.
A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li, Yanmei Qiu, Yunlei Yang, Yanhao Wei, Haokun Peng, Longhai Zeng, Pengcheng Li, Rentang Bi, Bo Hu   +8 more
wiley   +1 more source

Ablation of neurogenesis attenuates recovery of motor function after focal cerebral ischemia in middle-aged mice. [PDF]

PLoS ONE, 2012
Depletion of neurogenesis worsens functional outcome in young-adult mice after focal cerebral ischemia, but whether a similar effect occurs in older mice is unknown.
Fen Sun, Xiaomei Wang, Xiaoou Mao, Lin Xie, Kunlin Jin   +4 more
doaj   +1 more source

Flipping the Switch: MeCP2‐Mediated Lactylation Rewires Microglial Metabolism and Inflammation via the HK2/mTOR Axis in Poststroke Neuroinflammation

Advanced Science, EarlyView.
Stroke‐induced lactate accumulation promotes p300‐mediated lactylation of methyl‐CpG binding protein 2 (MeCP2) at lysine 210, which reprograms microglial metabolism toward glycolysis and activates the hexokinase 2 (HK2)/mTOR axis. This cascade promotes proinflammatory responses and impairs neurofunctional outcomes.
Zengyu Zhang, Shanshan Huang, Yong Wang, Zhiwen Jiang, Zhuohang Liu, Chenran Wang, Rong Ji, Yiwen Yuan, Xueyu Mao, Kaicheng Yang, Huicong Niu, Yanqin Gao, Jing Zhao   +12 more
wiley   +1 more source

Bio‐Inspired Micro‐Fin‐Assisted Multi‐Modal Vascular Intervention

Advanced Science, EarlyView.
A magnetic guidewire with a micro‐fin–integrated tip is introduced for multimodal cardiovascular navigation. The micro‐fins exploit fluid drag to augment magnetic torque, enabling bifurcation traversal at 15 mT, tolerating 45° misalignment, bidirectional crawling, and buckle self‐correction.
Xu Liu, Qiang Luo, Zhuoqun Cao, Hongde Li, Xi Chen, Hong Wang, Mao Chen, Ziyu Ren, Wenqi Hu   +8 more
wiley   +1 more source

A novel model of ischemia in rats with middle cerebral artery occlusion using a microcatheter and zirconia ball under fluoroscopy [PDF]

, 2021
Teppei Komatsu, Hiroki Ohta, Haruhiko Motegi, Junichi Hata, Koshiro Terawaki, Makoto Koizumi, Kanako Muta, Hirotaka James Okano, Yasuyuki Iguchi   +8 more
openalex   +1 more source