Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Evolving Food Choices Among the Urban Indian Middle-Class: A Qualitative Study. [PDF]
Kumar GS, Kulkarni M, Rathi N.
europepmc +1 more source
The urban middle class in the instability of new democracies [PDF]
The recent revolts of the middle class in the national capitals of the Philippines and Thailand have raised a new question about democratic consolidation.
Kawanaka, Takeshi
core
Why Middle Class Americans Need Health Reform [PDF]
[Excerpt] Middle class Americans across the country are demanding health reform. Businesses and families are struggling under the increasing financial burden of rising health care costs, and even middle class Americans with health insurance are ...
Office of the Vice President
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Construction d'enquête et définition des groupes sociaux
In this paper, we study Jerrold Seigel's book through the prism of the issue of the relation between the way the author constructs his object and that of the inquiry.
Cyprien Tasset
doaj
Life before limb: What about life after limb loss? A perspective from a low middle class income country: A Surgical Perspective. [PDF]
Siddiqui NA, Pirzada A, Virji SN.
europepmc +1 more source
Who takes the cake Effects of ECB monetary policy across income classes [PDF]
This work provides evidence on the effects of monetary policy on the income class structure via stimulating economic activity and employment in Eurozone countries over the period 2007Q32016Q1.
Barcena-Martin, Elena Maria +2 more
core
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
The emergent middle classes in Timor-Leste and Melanesia: conceptual issues and developmental significance [PDF]
The concept of an emerging middle class provides a useful entry point for understanding significant developmental and political transformations in Timor-Leste and Melanesia and is important for informing development policies.
John Cox, Julien Barbara, Michael Leach
core +1 more source

