Single-Cell Transcriptomes Reveal a Complex Cellular Landscape in the Middle Ear and Differential Capacities for Acute Response to Infection. [PDF]
Single-cell transcriptomics was used to profile cells of the normal murine middle ear. Clustering analysis of 6770 transcriptomes identified 17 cell clusters corresponding to distinct cell types: five epithelial, three stromal, three lymphocyte, two ...
Draf, Clara +6 more
core
Review of otitis media microbiome studies: What do they tell us?
Objectives To provide a state of the art review on accruing studies focused on defining the middle ear microbiome, highlighting the relationship of the microbiome to disease pathophysiology.
Juan Carlos Nogues +2 more
doaj +1 more source
Multi-color reflectance imaging of middle ear pathology in vivo [PDF]
Otoscopic examination using white-light illumination has remained virtually unchanged for well over a century. However, the limited contrast of white-light otoscopy constrains the ability to make accurate assessment of middle ear pathology and is subject
Barman, Ishan +7 more
core +1 more source
Middle ear mucosal regeneration by tissue-engineered cell sheet transplantation
Nose tissue that helps the ear heal Transplanting a sheet of cells from the nose to the middle ear could improve postoperative prognosis for middle ear inflammatory conditions.
Kazuhisa Yamamoto +7 more
doaj +1 more source
Capillary hemangioma of tympanic cleft [PDF]
We present an extensive capillary hemangioma of right ear in an 11-year-old child involving external auditory canal, middle ear and mastoid. Patient was presented with chronic purulent discharge and aural mass in right ear. The Computarize tomography (CT)
Bhandary, Sangita +3 more
core +1 more source
Cochlear-bone wave can yield a hearing sensation as well as otoacoustic emission
A hearing sensation arises when the elastic basilar membrane inside the cochlea vibrates. The basilar membrane is typically set into motion through airborne sound that displaces the middle ear and induces a pressure difference across the membrane.
Reichenbach, T., Tchumatchenko, T.
core +1 more source
The role of fibroblast growth factors in cell and cancer metabolism
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley +1 more source
A STUDY ON CHRONIC OTITIS MEDIA ACTIVE MUCOSAL TYPE WITH SINUSITIS AS FOCAL SEPSIS [PDF]
AIM : To establish the role of Sinusitis as Focal sepsis in Chronic Otitis media active mucosal disease, to emphasizethe need of proper diagnostic endoscopic evaluation and improvement in middle ear mucosal disease status afterfunctional endoscopic sinus
Gopalakrishnan, Shankaranarayanan +1 more
core +1 more source
Integration of 3D-printed middle ear models and middle ear prostheses in otosurgical training. [PDF]
Background In otosurgical training, cadaveric temporal bones are primarily used to provide a realistic tactile experience. However, using cadaveric temporal bones is challenging due to their limited availability, high cost, and potential for infection ...
Lähde S +4 more
europepmc +2 more sources
Hyperostotic tympanic bone spicules in domestic and wild animal species [PDF]
Hyperostotic tympanic bone spicules (HTBS), or "mucoperiosteal exostoses" (ME, syn.) are small, globular (>= 1 mm in diameter), mostly stalked and drumstick-like, bony structures, which arise from the inner wall of the tympanic bulla and project into the
Blutke, A +5 more
core +2 more sources

