Analysis of mRNA m6A modification and mRNA expression profiles in middle ear cholesteatoma [PDF]
Frontiers in Genetics, 2023 Introduction: Middle ear cholesteatoma is characterized by the hyperproliferation of keratinocytes. In recent decades, N6-methyladenosine (m6A) modification has been shown to play an essential role in the pathogenesis of many proliferative diseases ...
Shumin Xie +6 more
doaj +2 more sources
Middle ear cholesteatoma in two cats diagnosed with the aid of video-otoscopy [PDF]
Journal of Feline Medicine and Surgery Open Reports, 2023 Case series summary The present report describes middle ear cholesteatoma in two cats and also the use of video-otoscopy and flushing to assist with the diagnosis.
Cristiane Bazaga Botelho +5 more
doaj +2 more sources
Immunohistochemical localization of d‐β‐aspartic acid in congenital and acquired middle ear cholesteatoma [PDF]
Laryngoscope Investigative Otolaryngology, 2022 Objective/Hypothesis Middle ear cholesteatoma is characterized by abnormal growth of the keratinizing squamous epithelium of the temporal bone. d‐β‐aspartic acid is the major isomer of d‐aspartic acid found in elderly tissue.
Shiori Kitaya +12 more
doaj +2 more sources
N6-methyladenosine methylation analysis of circRNAs in acquired middle ear cholesteatoma [PDF]
Frontiers in GeneticsIntroductionMiddle ear cholesteatoma is a chronic middle ear disease characterized by severe hearing loss and adjacent bone erosion, resulting in numerous complications.
Jun He +5 more
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Microarray analysis and functional prediction of differentially expressed circular RNAs in acquired middle ear cholesteatoma [PDF]
BioMedical Engineering OnLine, 2021 Background Middle ear cholesteatoma is characterized by hyper-proliferation of keratinocytes. Circular RNA (circRNA) plays an essential role in the pathogenesis of many proliferative diseases.
Shumin Xie +4 more
doaj +2 more sources
Identification of miRNA expression profile in middle ear cholesteatoma using small RNA-sequencing [PDF]
BMC Medical GenomicsBackground The present study aims to identify the differential miRNA expression profile in middle ear cholesteatoma and explore their potential roles in its pathogenesis.
Mengyao Xie +9 more
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Animal Models of Middle Ear Cholesteatoma [PDF]
BioMed Research International, 2011 Middle ear acquired cholesteatoma is a pathological condition associated with otitis media, which may be associated with temporal bone resorption, otorrhea and hearing loss, and occasionally various other complications.
Koji, Takehiko +2 more
core +7 more sources
Endoscopic ear surgery in middle ear cholesteatoma
Laparoscopic, Endoscopic and Robotic Surgery, 2021 Objective: Endoscope has been used as diagnostic tool for recidivism and as an adjunct to microscopic technique in the management of cholesteatoma. At present transcanal endoscopic ear surgery (TEES) is being used as a minimally invasive alternative for ...
Satish Nair +7 more
doaj +2 more sources
Incidence and trends of middle ear cholesteatoma surgery and mastoidectomy in Australia—A national hospital morbidity database analysis [PDF]
Laryngoscope Investigative Otolaryngology, 2022 Objective To investigate the incidence of middle ear cholesteatoma surgery and assess trends in mastoidectomy procedures in Australia. Study design Cross‐sectional population‐based study using data from the National Hospital Morbidity Database.
Jonathan Li +3 more
doaj +2 more sources
Philippine Journal of Otolaryngology Head and Neck Surgery, 2021 Objective: To determine the stage of middle ear cholesteatoma of patients who underwent middle ear surgery at the Southern Philippines Medical Center from January to December 2019, based on European Academy of Otology and Neurotology / Japan ...
Dominador Toral, Chris Robinson Laganao
doaj +1 more source