Results 1 to 10 of about 9,901 (211)

Microarray analysis and functional prediction of differentially expressed circular RNAs in acquired middle ear cholesteatoma [PDF]

BioMedical Engineering OnLine, 2021
Background Middle ear cholesteatoma is characterized by hyper-proliferation of keratinocytes. Circular RNA (circRNA) plays an essential role in the pathogenesis of many proliferative diseases.
Shumin Xie, Li Jin, Tuanfang Yin, Jihao Ren, Wei Liu   +4 more
doaj   +4 more sources

Analysis of mRNA m6A modification and mRNA expression profiles in middle ear cholesteatoma [PDF]

Frontiers in Genetics, 2023
Introduction: Middle ear cholesteatoma is characterized by the hyperproliferation of keratinocytes. In recent decades, N6-methyladenosine (m6A) modification has been shown to play an essential role in the pathogenesis of many proliferative diseases ...
Shumin Xie, Li Jin, Jun He, Jinfeng Fu, Tuanfang Yin, Jihao Ren, Wei Liu   +6 more
doaj   +2 more sources

Isolated Congenital Mastoid Cholesteatoma with no Involvement of Aditus Ad Antrum and Middle Ear [PDF]

Clinical Medicine Insights: Case Reports, 2021
Cholesteatoma is a non-neoplastic, keratinized squamous epithelial lesion that affects the temporal bone. The middle ear is the most frequent, while the isolated cholesteatoma of the mastoid is rare.
Pace Annalisa, Iannella Giannicola, Rossetti Valeria, Messineo Daniela, Visconti Irene Claudia, Polimeni Roberta, Milani Alessandro, Magliulo Giuseppe   +7 more
doaj   +2 more sources

Immunohistochemical localization of d‐β‐aspartic acid in congenital and acquired middle ear cholesteatoma [PDF]

Laryngoscope Investigative Otolaryngology, 2022
Objective/Hypothesis Middle ear cholesteatoma is characterized by abnormal growth of the keratinizing squamous epithelium of the temporal bone. d‐β‐aspartic acid is the major isomer of d‐aspartic acid found in elderly tissue.
Shiori Kitaya, Ryoukichi Ikeda, Jun Suzuki, Hidetoshi Oshima, Yuri Nomura, Yusuke Kusano, Nobuo Ohta, Tetsuaki Kawase, Kazue Ise, Kazuhiro Murakami, Yasuhiro Nakamura, Hironobu Sasano, Yukio Katori   +12 more
doaj   +2 more sources

Middle ear cholesteatoma in two cats diagnosed with the aid of video-otoscopy [PDF]

Journal of Feline Medicine and Surgery Open Reports, 2023
Case series summary The present report describes middle ear cholesteatoma in two cats and also the use of video-otoscopy and flushing to assist with the diagnosis.
Cristiane Bazaga Botelho, Rafaella Tortoriello, Sandra Nogueira Koch, Natália Lôres Lopes, Ronaldo Lucas, Julio Israel Fernandes   +5 more
doaj   +2 more sources

N6-methyladenosine methylation analysis of circRNAs in acquired middle ear cholesteatoma [PDF]

Frontiers in Genetics
IntroductionMiddle ear cholesteatoma is a chronic middle ear disease characterized by severe hearing loss and adjacent bone erosion, resulting in numerous complications.
Jun He, Ahmad Mahmoudi, Jacqueline Yao, Qiulin Yuan, Jinfeng Fu, Wei Liu   +5 more
doaj   +2 more sources

Optical Imaging With a High-Resolution Microendoscope to Identify Cholesteatoma of the Middle Ear [PDF]

, 2013
Objectives/Hypothesis: High-resolution optical imaging is an imaging modality that allows visualization of structural changes in epithelial tissue in real time.
Ahn, Ananthapadmanabhan, Bragulla, Broekaert, Broekaert, Bujia, Edelstein, Ferguson, Habesoglu, Janssen, Kiesslich, Luzzati, Muldoon, Muldoon, Muldoon, Olszewska, Polglase, Roblyer, Roger, Rolland, Sheehy, Smouha, Smouha, Svane-Knudsen, Vartiainen, Vila   +25 more
core   +3 more sources

Identification of miRNA expression profile in middle ear cholesteatoma using small RNA-sequencing [PDF]

BMC Medical Genomics
Background The present study aims to identify the differential miRNA expression profile in middle ear cholesteatoma and explore their potential roles in its pathogenesis.
Mengyao Xie, Qi Tang, Shu Wang, Xiaowu Huang, Zhiyuan Wu, Zhijin Han, Chen Li, Bin Wang, Yingying Shang, Hua Yang   +9 more
doaj   +2 more sources

The value of otoendoscopy in the management of middle ear cholesteatoma

Journal of Research in Medical Sciences, 2015
Background: The surgical management of cholesteatoma is a controversial issue, particularly regarding intact-canal-wall mastoidectomy (ICWM) versus canal-wall-down mastoidectomy (CWDM).
Sayed Hamidreza Abtahi, Farzaneh Abootalebian, Mehrdad Rogha, Nezamoddin Berjis   +3 more
doaj   +2 more sources

Fusion of computed tomography and diffusionweighted magnetic resonance images for detection of primary, residual and recurrent cholesteatoma of the middle ear

Alʹmanah Kliničeskoj Mediciny, 2016
Background:  At present,  computed  tomography  (CT)  is recognized  as  method for primary diagnosis of middle ear disorders. More accurate diagnosis  of  cholesteatoma  is based  on  a  sequence  of non-echo   planar  diffusion-weighted magnetic ...
E. A. Stepanova, M. V. Vishnyakova, A. S. Abramenko, V. I. Sambulov   +3 more
doaj   +4 more sources