Results 91 to 100 of about 3,910,096 (316)

Synthesis and cellular bioactivities of novel isoxazole derivatives incorporating an arylpiperazine moiety as anticancer agents

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2018
In our endeavour towards the development of effective anticancer therapeutics, a novel series of isoxazole-piperazine hybrids were synthesized and evaluated for their cytotoxic activities against human liver (Huh7 and Mahlavu) and breast (MCF-7) cancer ...
Burcu Çalışkan   +5 more
doaj   +1 more source

Ortadoğu'da terör : Al-Qaeda ve Hamas mukayesesi.

open access: yes, 2019
The aim of this thesis is to analyze al-Qaeda and Hamas, which are two of the organizations that come to mind when it comes to terrorist activities in Middle East, compare them under headings including their ideologies, goals, spheres of influence, their
Temel, Sevinç Ebru
core  

Entegrasyon politikalarında eğitimin rolü : Suriye mülteci krizi sonrası İsveç, Almanya Türkiye karşılaştırması.

open access: yes, 2020
This study aims to produce a comparative research on integration policies of Sweden, Germany, and Turkey that host remarkable number of Syrians after the crisis in Syria which is considered as the biggest humanitarian and refugee crisis of our time. This
Erşekerci, Nesibe Burcu
core  

Comprehensive Characterization of 98 Chinese Cases of Genetic Creutzfeldt‐Jakob Disease With T188K Mutation

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li   +11 more
wiley   +1 more source

Kudüs değil, Şam: Suriye savaşı’ndaki (2011 –2017) Lübnan’dan gelen Filistinli cihatçılar.

open access: yes, 2019
Ongoing Syrian War is one of the most important historical event for both the Middle East and the world in recent history. Regional and international powers with their proxies has shaped not only Syrian politics, economy, and international relations, but
Çete, Erman
core  

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig   +9 more
wiley   +1 more source

Shading Effect of Transparent Photovoltaic Panels on Crops Underneath Agrivoltaic Systems

open access: yesAgriVoltaics Conference Proceedings
Agrivoltaic systems combine soil-grown crops with photovoltaic (PV) panels erected several meters above the ground. Combining solar panels and food crops on the same land can maximize land utilization.
Nasim Seyedpour Esmaeilzad   +5 more
doaj   +1 more source

Bi‐ and Mono‐Allelic RFC1 Expansion in a North American Cohort With Idiopathic Axonal Neuropathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective RFC1 biallelic repeat expansion is increasingly recognized as a cause of chronic idiopathic axonal polyneuropathy (CIAP), but it remains challenging to know who to test. This study aims to determine the prevalence of biallelic and monoallelic RFC1 expansions and their corresponding neuropathy phenotypes in CIAP patients and identify ...
Amro M. Stino   +25 more
wiley   +1 more source

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau   +11 more
wiley   +1 more source

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif   +17 more
wiley   +1 more source

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