Results 41 to 50 of about 3,910,096 (316)

Significant Serum Progesterone Variations on the Day of Final Oocyte Maturation in Stimulated IVF Cycles

Frontiers in Endocrinology, 2019
Objective: To evaluate intraday serum progesterone levels on the day of final oocyte maturation in women undergoing ovarian stimulation in a GnRH-antagonist protocol.Study design, size, and duration: The study was done as a prospective observational ...
Upma Shanker, Barbara Lawrenz, Barbara Lawrenz, Leif Bungum, Leyla Depret Bixio, Francisco Ruiz, Carol Coughlan, Human M. Fatemi, Human M. Fatemi, Human M. Fatemi   +9 more
doaj   +1 more source

Assessment of process capabilities in transition to a data‐driven organisation: A multidisciplinary approach

IET Software, 2021
The ability to leverage data science can generate valuable insights and actions in organisations by enhancing data‐driven decision‐making to find optimal solutions based on complex business parameters and data.
Mert O. Gökalp, Kerem Kayabay, Ebru Gökalp, Altan Koçyiğit, P. Erhan Eren   +4 more
doaj   +1 more source

Middle East Respiratory Syndrome [PDF]

New England Journal of Medicine, 2017
The Middle East respiratory syndrome is caused by a coronavirus that was first identified in Saudi Arabia in 2012. Periodic outbreaks continue to occur in the Middle East and elsewhere. This report provides the latest information on MERS.
Arabi, Yaseen M., Balkhy, Hanan H., Hayden, Frederick G., Bouchama, Abderrezak, Luke, Thomas, Baillie, John; id_orcid 0000-0001-5258-793X, Al-Omari, Awad, Hajeer, Ali H., Senga, Mikiko, Denison, Mark R., Nguyen-Van-Tam, Jonathan S., Shindo, Nahoko, Bermingham, Alison, Chappell, James D., Van Kerkhove, Maria D., Fowler, Robert A.   +15 more
openaire   +3 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

A Possible Submarine Landslide and Associated Tsunami at the Northwest Nile Delta, Mediterranean Sea [PDF]

Oceanography, 2014
A hypothetical landslide tsunami at the Nile Delta in the Eastern Mediterranean Sea is modeled in order to study hazards it would pose to the region. The methodology used is based on numerical simulation of the generation and propagation of a realistic ...
Ahmet Yalciner, Andrey Zaytsev, Betul Aytore, Isil Insel, Mohammad Heidarzadeh, Rozita Kian, Fumihiko Imamura   +6 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Chaos from massive deformations of Yang-Mills matrix models

Journal of High Energy Physics, 2020
We focus on an SU(N ) Yang-Mills gauge theory in 0 + 1-dimensions with the same matrix content as the bosonic part of the BFSS matrix model, but with mass deformation terms breaking the global SO(9) symmetry of the latter to SO(5) × SO(3) × ℤ2 ...
K. Başkan, S. Kürkçüoğlu, O. Oktay, C. Taşcı   +3 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source