Results 61 to 70 of about 5,300,263 (357)

A Possible Submarine Landslide and Associated Tsunami at the Northwest Nile Delta, Mediterranean Sea [PDF]

open access: yesOceanography, 2014
A hypothetical landslide tsunami at the Nile Delta in the Eastern Mediterranean Sea is modeled in order to study hazards it would pose to the region. The methodology used is based on numerical simulation of the generation and propagation of a realistic ...
Ahmet Yalciner   +6 more
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Chaos from massive deformations of Yang-Mills matrix models

open access: yesJournal of High Energy Physics, 2020
We focus on an SU(N ) Yang-Mills gauge theory in 0 + 1-dimensions with the same matrix content as the bosonic part of the BFSS matrix model, but with mass deformation terms breaking the global SO(9) symmetry of the latter to SO(5) × SO(3) × ℤ2 ...
K. Başkan   +3 more
doaj   +1 more source

Burnout among healthcare providers in the complex environment of the Middle East: a systematic review

open access: yesBMC Public Health, 2019
Burnout is a syndrome characterized by emotional exhaustion, increased depersonalization, and a diminished sense of personal accomplishment due to chronic emotional stress at work.
Z. Chemali   +7 more
semanticscholar   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Recent Advances in the Vaccine Development Against Middle East Respiratory Syndrome-Coronavirus

open access: yesFrontiers in Microbiology, 2019
Middle East respiratory syndrome (MERS) is a deadly viral respiratory disease caused by MERS-coronavirus (MERS-CoV) infection. To date, there is no specific treatment proven effective against this viral disease.
Chean Yeah Yong   +4 more
semanticscholar   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Araştırma Görevlilerinin Bilim ve Bilimsel Etkinliklere İlişkin Algılarının Karşılaştırmalı Analizi

open access: yesAnkara Üniversitesi Eğitim Bilimleri Fakültesi Dergisi, 2014
Bu nicel çalışmada araştırma görevlilerinin bilime ve bilimsel etkinliklere ilişkin algıları araştırılmıştır. Daha ayrıntılı olarak bu çalışmada araştırma görevlilerinin bilim ve bilimsel etkinlikler hakkındaki görüşleri araştırma görevliliği statüsü (
Nuri KARA   +3 more
doaj  

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