Results 51 to 60 of about 3,719,166 (302)

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

open access: yesFEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima   +4 more
wiley   +1 more source

Some Observations on the First Middle English Translation of the Revelation of John

open access: yesFilologia Germanica
The Revelation of John represents one of the most popular texts of medieval Europe. This popularity, undoubtedly fuelled by fears and expectations of the year one thousand, is reflected not only in the presence of millenarian themes in contemporary ...
Letizia Vezzosi
doaj   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

open access: yesFEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori   +8 more
wiley   +1 more source

The Dynamics of Postnominal Adjectives in Middle English

open access: yesAnglica. An International Journal of English Studies, 2022
Middle English was a period of transition between the free word order of Old English, with functional variation of adjective form and position with respect to the head noun, and the fixed prenominal placement of single attributive adjectives in Modern ...
Veronika Volná, Pavlína Šaldová
doaj   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Sawyer, Daniel. 2024. How to Read Middle English Poetry. Oxford: Oxford University Press. Pp. 240. ISBN 9780198895237.

open access: yesSELIM
Book review of Sawyer, Daniel. 2024. How to Read Middle English Poetry. Oxford: Oxford University Press. Pp. 240. ISBN 9780198895237.
Laurie Atkinson
doaj   +3 more sources

A Comparative Investigation of Anaphoric Reference Devices in Anglo-Norman and Middle English Personal Letters

open access: yesStudia Anglica Posnaniensia, 2022
This paper compares the use of anaphoric reference terms, such as le dit (and its English equivalent the said), a characteristic feature of ‘curial style’, in Anglo-Norman (hence AN) and Middle English (hence ME) personal letters.
Marcus Imogen
doaj   +1 more source

Acoustic Measures Capture Speech Dysfunction in Spinocerebellar Ataxia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxias (SCA) are hereditary cerebellar degenerative disorders with a common feature of dysarthria, involving impaired phonatory and articulatory control of speech, thereby affecting social communication. In this study, we investigated whether acoustic measures could objectively measure speech dysfunction and identify
Zena Fadel   +5 more
wiley   +1 more source

The Manuscripts of the Middle English Lay Folks’ Mass Book in Context

open access: yesStudia Anglica Posnaniensia, 2021
This paper, part of a long-term programme of research into the forms and functions of the vernacular in late medieval liturgical practice in England, offers a “cultural map” of the Middle English poem known as The Lay Folks’ Mass Book (LFMB ...
Smith Jeremy J.
doaj   +1 more source

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