Results 141 to 150 of about 2,650,610 (297)
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
On the stress-sum index of the middle and central graph of a graph
Boletim da Sociedade Paranaense de MatemáticaRanking molecular chemical compounds or large networks is a complex task due to their inherent degeneracy. Centrality measures helps to estimate the rank of each molecular chemical graph. One such centrality measure is the stress centrality, which quantifies the number of shortest paths passing through a given vertex.
null Niveditha +2 more
openaire +1 more source
The social–ecological model of depressive symptoms in middle aged in China: a network analysis
BMC Public HealthBackground Depression in middle-aged individuals is influenced by multiple factors; however, research focusing on this demographic remains limited. The social-ecological system framework explores how interactions among individual characteristics, social ...
Guanghui Shen +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
A characterization of middle graphs and a matroid associated with middle graphs of hypergraphs [PDF]
Fundamenta Mathematicae, 1983 openaire +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Partial domination of middle graphs
For any graph $G=(V,E)$, a subset $S\subseteq V$ is called {\it an isolating set} of $G$ if $V\setminus N_G[S]$ is an independent set of $G$, where $N_G[S]=S\cup N_G(S)$, and {\it the isolation number} of $G$, denoted by $ι(G)$, is the size of a smallest isolating set of $G$. In this article, we show that the isolation number of the middle graph of $G$
Zhang, Shumin +2 more
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Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Scientific ReportsThis study focuses on the Yangtze River Economic Belt in Hubei Province, addressing ecosystem service degradation and ecological risks under rapid urbanization. An integrated “Importance–Sensitivity–Circuit Theory–Graph Theory” framework was developed to
Junfeng Zeng, Shushen Li
doaj +1 more source