Results 51 to 60 of about 3,253,971 (341)

A Systematic Review of Evidence on the Clinical Effectiveness of Surveillance Imaging in Children With Medulloblastoma and Ependymoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Surveillance imaging aims to detect tumour relapse before symptoms develop, but it's unclear whether earlier detection of relapse leads to better outcomes in children and young people (CYP) with medulloblastoma and ependymoma. This systematic review aims to identify relevant literature to determine the efficacy of surveillance magnetic ...
Lucy Shepherd, Melissa Taylor, Helen Fulbright, Bob Phillips   +3 more
wiley   +1 more source

The genealogy of the king of Scots as charter and panegyric [PDF]

, 2019
When we think of genealogies in medieval Scotland our minds might turn at once to Gaelic, the Celtic language that was spoken in the Middle Ages from the southern tip of Ireland to the northernmost coast of Scotland. This is not unnatural.
Broun, Dauvit
core  

The sound values of the signs Gardiner D1 (Head) and T8 (Dagger) [PDF]

, 2004
It is argued that the evidence in the Books of the Netherworld attested in the New Kingdom doubtlessly proves that the signs [Gardiner D1, head] and [Gardiner T8, dagger] corresponded to dp /t’(V)p/ and dpj>dpï /t’(V)p(V)(j)/ respectively, both with ...
Werning, Daniel A.
core   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

The making of the Ragman Roll: the work of the notary [PDF]

, 2011
Between the middle of May and the end of August 1296, during the course of a royal progress through the kingdom of Scots, via an eastern coastal route, having militarily asserted his authority over the leading nobles of Scotland, Edward I received ...
Davies, J.R.
core  

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

The value of a human life in ancient Egyptian religion at the turn of the 3rd –2nd millennia BC

Шаги
The author explores the ancient Egyptian religion’s perspective on value of a human life during the latter part of the Old Kingdom, the First Intermediate Period, and the Middle Kingdom. Polytheistic ritualistic “communal” religions, where ethics did not
A. E. Demidchik
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source