Results 61 to 70 of about 1,221,481 (353)
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Europe: So Many Languages, So Many Cultures [PDF]
, 2011 The number of different languages in Europe by far exceeds the number of countries. All European countries have national languages, and in nearly all of them there are minority languages as well, whereas all major languages have dialects.
Steinhauer, H. (Hein)
core +3 more sources
Insights into a long life without cancer: The case of the bowhead whale
Molecular Oncology, EarlyView.Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley +1 more source
Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion
FEBS Open Bio, EarlyView.Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng +2 more
wiley +1 more source
Business Competitiveness in Bahrain: A Synopsis [PDF]
Unbridled freedom to private business sector is a harbinger of business collapse and eventually the economic landscapes of nations. We have had ample examples very recently.
Pillai, K R
core +1 more source
Dimensions of authentic leadership in the Middle Eastern context: Are these leaders really authentic? [PDF]
, 2016 The economic crisis and the various business scandals have placed a call for leaders who are responsible, ethical, do not deceive others,and lead in an authentic way.
Marinakou, Evangelia, Nikolic, B
core
The sound values of the signs Gardiner D1 (Head) and T8 (Dagger) [PDF]
, 2004 It is argued that the evidence in the Books of the Netherworld attested in the New Kingdom doubtlessly proves that the signs [Gardiner D1, head] and [Gardiner T8, dagger] corresponded to dp /t’(V)p/ and dpj>dpï /t’(V)p(V)(j)/ respectively, both with ...
Werning, Daniel A.
core +1 more source
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
FEBS Open Bio, EarlyView.Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
, 2014 The evolution of RNA viruses such as HIV, Hepatitis C and Influenza virus occurs so rapidly that the viruses' genomes contain information on past ecological dynamics.
Drummond, Alexei J. +3 more
core +1 more source
Middle East respiratory syndrome coronavirus in pediatrics: a report of seven cases from Saudi Arabia [PDF]
, 2018 This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Al-Tawfiq, Jaffar A. +3 more
core +1 more source