Results 81 to 90 of about 3,253,971 (341)

Multipurpose heavy atom effects for organic solution room temperature-phosphorescence

open access: yesJPhys Materials
Heavy atom insertions are often used to increase spin–orbit coupling to enhance the performance of advanced emissive molecules. In this work we apply heavy atoms in both the linker (thiophene) and donor (phenoselenazine) groups of D-A emitters, and ...
Oguzhan Karakurt   +7 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Usāma ibn Munqidh and Crusader Law in the Twelfth Century [PDF]

open access: yes, 2013
International audienceThe major legal treatises of the Kingdom of Jerusalem all date from the thirteenth century, after the kingdom had largely been reconquered by its Muslim neighbours. There are no comparable sources for the first period of the kingdom
Bishop, Adam,
core   +1 more source

The British national minimum wage [PDF]

open access: yes, 2003
Great Britain has had statutory regulation of minimum pay for much of this century but never previously had a national minimum wage (NMW). This paper outlines the history of minimum wage regulation culminating in 1997 with the establishment of the Low ...
Metcalf, David
core   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

open access: yesFEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori   +8 more
wiley   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

open access: yesFEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng   +2 more
wiley   +1 more source

Les étrangers dans le royaume d’Arraphe

open access: yesPallas, 2017
Tablets excavated at Nuzi, Arraphe and Tell al-Fahhar provide evidence for the presence of foreigners in the Kingdom of Arraphe during the 15th and 14th centuries BC.
Brigitte Lion
doaj   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

open access: yesFEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi   +7 more
wiley   +1 more source

Land, freedom and the making of the medieval West [PDF]

open access: yes, 2006
In the course of the fifth and sixth centuries, barbarian warbands acquired property rights in the former provinces of the Roman west, in a process that established the broad structural characteristics of early medieval society in western Europe: that is
Innes, Matthew
core   +1 more source

Predicting and Comparing the Subjective Health Experience of Older Cancer Survivors and Non‐Cancer Survivors: A Modeling Approach

open access: yesAging and Cancer, EarlyView.
This study underscores the significant influence of frailty and vitality on the subjective health experience of older cancer survivors with acceptance and control emerging as salient mediators. These findings affirm the conceptual and empirical robustness of the model highlighting its potential utility in shaping future interventions for older cancer ...
Damien S. E. Broekharst   +4 more
wiley   +1 more source

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