Results 121 to 130 of about 11,398,859 (344)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Evolution, Middle Knowledge, and Theodicy
Forum Philosophicum, 2020 In this paper, I investigate the relationship between a nonlapsarian, evolutionary account of the origin of sin and the potential ramifications this might have for theodicy. I begin by reviving an early twentieth century evolutionary model of the origin of sin before discussing the most prominent objection which it elicits, namely, that if sin is ...
openaire +1 more source
Building Middle-Level Mathematics Teachers\u27 Capacities as Teachers and Leaders: The Math in the Middle Institute Partnership [PDF]
, 2009 This article describes professional development for middle-level mathematics teachers offered through the Math in the Middle Institute Partnership, a National Science Foundation-funded project to build teachers’ capacities to improve mathematics learning
Heaton, R. M. +2 more
core +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
NeuroImageProblem-solving strategies vary depending on the type of problem and aging. This study investigated the hemodynamic response measured by the changes in the oxyhemoglobin concentration (HbO), alpha frequency power, and their interrelation during problem ...
Mevhibe Saricaoglu +4 more
doaj +1 more source
Vision Statements and Road-Map Methodology for Knowledge Management Adoption [PDF]
The present paper describes the strategy of introducing future knowledge management system at farms. The FUTUREFARM and PREZEM projects strive to apply new knowledge management methods in arable farming where they guarantee an easy adaptation of the ...
Charvat, Karel +3 more
core +1 more source
Primary and secondary teachers shaping the science curriculum : the influence of teacher knowledge [PDF]
, 2003 This thesis reports on how primary and secondary teachers' knowledge influenced the implementation of a Year 1-10 science syllabus which was introduced into Queensland in 1999.
Keys, Philip Mark
core +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
ION GLODEANU, From the Theory of the Middle Class to the Theory of Elites [PDF]
Revista Română de Sociologie, 2008 The article presents a sketch of how the "conceptual field" was formed with respect to issues related to the formation and evolution of the middle class, of the changes of content and direction thereof in relation to the historical period in which they ...
OSCAR HOFFMAN
doaj
The effects of intellectual property protection on international knowledge contracting [PDF]
, 2005 Developing countries, and particularly, those with a growing technological capacity, expect foreign technology transfers to increase when strengthening their intellectual property protection (IPR) rights.
Bascavusoglu, E., Zuniga, Maria Pluvia
core +1 more source