Results 131 to 140 of about 11,398,859 (344)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Using Graphs to Show Connections [PDF]
, 2003 The purpose of this resource is to show how graphs of GLOBE data over time show the interconnectedness of Earth's system components at the local level.
The GLOBE Program, University Corporation for Atmospheric Research (UCAR)
core
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
San Francisco Bay Area KIPP Schools: A Study of Early Implementation and Achievement: Final Report [PDF]
, 2008 Examines the achievement results and operations of five Knowledge Is Power Program middle schools to assess the program's effectiveness, the role of leadership, implementation of the KIPP culture, design of curricula and instruction, and lessons ...
Alejandra Lopez-Torkos +4 more
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Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Journal of Awareness-Based Systems ChangeNhulunbuy, Yirrkala, Gunyaŋara and the surrounding Homelands in North East Arnhem Land in the Northern Territory of Australia are the home to Yolŋu people and have been for time immemorial. For Yolŋu, metaphor is powerful and living. Metaphors have been
Rarrtjiwuy Melanie Herdman +2 more
doaj +1 more source
Earth Knowledge Acquired by Middle School Students [PDF]
, 2008 Earth Knowledge Acquired by Middle School Students (EarthKAM), an education activity, allows middle school students to program a digital camera on board the International Space Station to photograph a variety of geographical targets for study in the ...
Ride, Sally
core +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Innovative Asia: Advancing the Knowledge-Based Economy - Highlights of the Forthcoming ADB Study Report [PDF]
, 2014 [Excerpt] The development of knowledge-based economies (KBEs) is both an imperative and an opportunity for developing Asia. It is an imperative to sustain high rates of growth in the future and an opportunity whereby emerging economies can draw from ...
Asian Development Bank
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