Results 81 to 90 of about 4,288,113 (308)
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Virginia Commonwealth University\u27s Program for K-6 and 6-8 Teachers: The Interdisciplinary B.S. in Science [PDF]
Virginia Commonwealth University (VCU) has very recently revised its requirements for the K-6 Certification to include a total of 21 hours in mathematics and science as well as a three credit hour methods course in mathematics and science.
Farley, R. W.
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
ObjectiveTo assess the level of health literacy and its influencing factors among middle school students aged 12‒18 years in Jing’an District, Shanghai, so as to provide a solid scientific foundation for further developing more targeted intervention ...
LYU Hongyun +5 more
doaj +1 more source
Using GLOBE Data to Analyze Land Cover [PDF]
The purpose of the resource is to develop hypotheses about which environmental factors are most important to plants.
The GLOBE Program, University Corporation for Atmospheric Research (UCAR)
core
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
A CiteSpace-based Analysis of Hotspots and Cutting-edge Trends in Mental Health among Middle School Students Research [PDF]
Background In recent years, mental health problems among middle school students in China have become increasingly prominent. Objective To explore the research hotspots, frontiers of research related to the mental health among middle school students, and ...
CHENG Qi, YU Wenbing, LI Keke, ZUO You, JIAO Qianxin, LIU Xinhao, GAO Lili
doaj +1 more source
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Transition to middle school: Self-concept changes.
Self-concept influences identity and the way that people behave, and it fluctuates over time. The main purpose of this study was to analyze fluctuations in the dimensions of self-concept as a function of gender, educational level, grade, age, physical ...
Wanesa Onetti +2 more
doaj +1 more source
The Beacon Community Centers Middle School Initiative: Final Report on Implementation and Youth Experience in the Initiative [PDF]
The report evaluates New York City's Beacon Middle School Initiative, which was launched to increase services to middle-grades youth through programs in academics, life skills, career awareness, civic engagement, physical health, and arts and culture ...
Christina A. Russell +3 more
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