Results 131 to 140 of about 1,817,169 (313)
PLoS ONEAcademic stress is associated with lower engagement in healthy behaviors, including physical exercise, among middle school students. Based on Self-Determination Theory, this study examines the association between academic stress and physical exercise ...
Kegang Zhao, Yichen Zhao, Weiqiang Xu
doaj +1 more source
Getting to Know Your Satellite Imagery and Study Site [PDF]
, 2003 The purpose of the resource is to introduce students to Landsat images and how to identify the land cover types within those images.
The GLOBE Program, University Corporation for Atmospheric Research (UCAR)
core
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Implications of Trauma-Sensitive Practices at the Middle Level [PDF]
, 2019 This essay provides a broad overview of adverse childhood experiences and their impact on the middle level learner. Through a literature review, the author finds points of intersection between current research on traumatized students, best practices for ...
Dotson Davis, Lauren
core +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Modeling Your Water Balance [PDF]
, 2003 The purpose of this resource is to model a soil's water storage over a year. Students will model the changes in soil water storage over a year.
The GLOBE Program, UCAR (University Corporation for Atmospheric Research)
core
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
A Preliminary Analysis of the Supply and Demand for Middle School Mathematics and Science Teachers in Virginia [PDF]
, 1999 Virginia Colleges and Universities have a major challenge to produce educated elementary and middle school students. The magnitude of this challenge can be measured by studying the number of current teachers in each grade in Virginia and the anticipated ...
Sigler, J. A.
core +1 more source
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source