Results 71 to 80 of about 1,817,169 (313)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Southern Disclosure: One Southern-and-Queer Middle School Teacher’s Narrative [PDF]

, 2018
This narrative inquiry is an autoethnographical account of one queer-identified middle school teacher\u27s career trajectory in the southern United States, and his struggle to navigate disclosure of his identity to students. Using a qualitative lens, the
Cain, Leia K, Coker, Jonathan M
core   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

The effect of special exercises according to the principle of re-training in the development of kinesthetic perception among middle school students

الرياضة المعاصرة, 2020
The importance of research that has manifested in raising the level of perception and its different types for students in the intermediate stages of education using a method and principle from the principles of mathematical training science is repeated ...
Dr. Shaimaa Ali
doaj   +1 more source

Eliminating Social Homelessness: Providing a Home to Grow [PDF]

, 2016
Middle school students who belong to marginalized identity groups often experience alienation and isolation. These feelings are compounded for multi-marginalized students who experience social homelessness–a term Harrison (2015) uses to describe students
Akos, Patrick, Duquette, Kevin, Harrison, Rydell   +2 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Effects of Parental Marital Status on Negative Emotions and Nonsuicidal Self-injury Behaviors in Middle School Students: a Multicenter Cross-sectional Study [PDF]

Zhongguo quanke yixue
Background Effects of parental marital status on nonsuicidal self-injury (NSSI) behaviors and negative emotions in adolescents have been rarely reported, and the existing research sample size is relatively small.
REN Xiaohong, CEN Yu, LUO Jing, ZHOU Yuling, HE Jinlong, LIN Cen, WU Dapeng, LUO Jiaming
doaj   +1 more source

Harsh Realities: The Experiences of Transgender Youth in Our Nation's Schools [PDF]

, 2009
Using data from GLSEN's fifth National School Climate Survey, this report documents the school experiences of 295 transgender middle and high school students and finds that these students face extremely high levels of victimization, even more so than ...
Elizabeth M. Diaz, Emily A. Greytak, Joseph G. Kosciw   +2 more
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

“Boy Crisis” or “Girl Risk”? The Gender Difference in Nonsuicidal Self-Injurious Behavior Among Middle-School Students in China and its Relationship to Gender Role Conflict and Violent Experiences

American Journal of Men's Health, 2018
Purpose: We attempted to test if there were gender differences in nonsuicidal self-injurious (NSSI) behaviors among Chinese middle-school students, and analyze the impact of gender role conflict and violent experiences on these behaviors among middle ...
Xueyan Yang PhD, Moye Xin MD Candidate
doaj   +1 more source