Results 111 to 120 of about 1,400,953 (307)

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Türkiye'de kapitalist gelişme ve islami sermayenin yükselişi.

, 2016
Islamic capital not only has a central place in the economic, political and cultural agenda of Turkey but also have implications for the rest of the Middle East region as a role model contemporarily.
Kabacıoğlu, Hilal
core  

Rethinking cardiovascular prevention beyond short term risk scores in low and middle income countries

Discover Public Health
Cardiovascular disease remains the leading cause of death worldwide, accounting for more than 20 million deaths each year, over 75% of which occur in low- and middle-income countries (LMICs).
Stefano Cacciatore, Domenico Mario Giamundo, Luigi Spadafora, Marco Bernardi, Michele Golino, Stefano Figliozzi, Francesco Perone, Giuseppe Biondi-Zoccai, Michael D. Shapiro, Pierre Sabouret, Emanuele Marzetti, Francesco Landi, Matteo Tosato   +12 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Transforming middle years education

This chapter focuses on school reform and sustainable practices in middle years education. The author explores the concepts of innovative disruption and transformation as they apply to educational change.
Pendergast, Donna
core   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

The Middle Term

, 1969
Not the January inter-term, but the middle term in the syllogism of ...
Rediger, Milo A.
core  

Coping with verbal and social bullying in middle school [PDF]

, 2014
Becoming a victim of verbal and social bullying in middle school can lead to illness, psychological stress, and maladjustment. The coping strategies that students utilize when they are bullied may influence the likelihood and severity of these negative
Almeida, Angela, David Brandwein, Donoghue, Christopher, Angela Almeida, Christopher Donoghue, Gabriela Rocha, Brandwein, David, Callahan, Ian, Rocha, Gabriela, Ian Callahan   +9 more
core  

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Is body mass index before middle age related to coronary heart disease risk in later life?

, 2009
Objective: Although obesity beginning early in life is becoming more common, its implications for coronary heart disease (CHD) risk in later life remain uncertain.
Orfei, L, Osmond, C, Owen, C.G., Cook DG, Whincup, PH, Whincup, P.H., Rudnicka, A.R., Osmond C, A K Wathern, Chou, QA, Eriksson, JG, L Orfei, Eriksson, J.G., C Osmond, Kaye, SJ, D G Cook, Kaye, S.J., Wathern AK, C G Owen, Q-A Chou, Kaye SJ, J G Eriksson, Rudnicka, AR, Wathern, AK, A R Rudnicka, Rudnicka AR, Owen CG, Chou QA, Whincup PH, Eriksson JG, Wathern, A.K., Orfei L, S J Kaye, Cook, D.G., Chou, Q-A., Owen, CG, Cook, DG, P H Whincup, Osmond, C., Orfel, L.   +39 more
core   +1 more source