Results 131 to 140 of about 4,582,425 (343)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Associations of hospital volume and hospital competition with short-term, middle-term and long-term patient outcomes after breast cancer surgery: a retrospective population-based study. [PDF]

BMJ Open, 2022
van der Schors W, Kemp R, van Hoeve J, Tjan-Heijnen V, Maduro J, Vrancken Peeters MJ, Siesling S, Varkevisser M.   +7 more
europepmc   +1 more source

Middle Ear Implants – Long Term Results and Indication

, 2017
88.
Lenarz, T, Maier, H
openaire   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Neurophysiological and neuroinflammatory adaptations to seizure activity in aging

Neurobiology of Disease
The pathophysiological impact of late-onset seizures on the brain is not well understood. Here, we investigated whether an initial pattern of generalized seizures (GS) with an electrographically defined ictal-interictal continuum, occurring at middle age
Alicia Janvier, Noemie Cresto, Cristina Nistreanu, Athenais Genin, Tristan Moujellil-Legagneur, Magalie Mathias, Mathieu Vitalis, Paolo Fabene, Edoardo Parrella, Charleine Zussy, Etienne Audinat, Laurent Givalois, Nicola Marchi   +12 more
doaj   +1 more source

Nutrients in waters on the inner shelf between Cape Charles and Cape Hatteras [PDF]

The distribution of nutrients in the shelf waters of the southern tip of the Middle Atlantic Bight was investigated. It is concluded that the outflow of freshwater from the Chesapeake Bay is a potential source of nutrients to the adjacent shelf waters ...
Todd, J. F., Wong, G. T. F.
core   +1 more source

Intervention Effect of Long-Term Aerobic Training on Anxiety, Depression, and Sleep Quality of Middle School Students With Depression After COVID-19 [PDF]

, 2021
Lin Luo, Naiqing Song, Hao Yang, JiaHong Huang, Ling Zhou, Liping Zhang   +5 more
openalex   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Long-term studies of the summer wind in the mesosphere and lower thermosphere at middle and high latitudes

, 2023
Juliana Jaen, Toralf Renkwitz, Huixin Liu, Christoph Jacobi, Robin Wing, Aleš Kuchař, Masaki Tsutsumi, Njål Gulbrandsen, Jorge L. Chau   +8 more
openalex   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source