Results 141 to 150 of about 4,582,425 (343)
Early and Middle-Term Results and Anticoagulation Strategy after Left Atrial Appendage Exclusion Using an Epicardial Clip Device. [PDF]
Ann Thorac Cardiovasc Surg, 2021 Yoshimoto A +5 more
europepmc +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Technological Singularity: A Nuanced and Contextual Approach to Potential Scenarios
RUDN Journal of PhilosophyIn this text it is discussed the concept of Technological Singularity. This concept, which is understood in the academic literature as a hypothetical scenario in which AI becomes uncontrollable, is one of the most recurrent subjects in Philosophy of ...
Adrià Harillo Pla
doaj +1 more source
The effects of solar particle events on the middle atmosphere [PDF]
Solar particle events (SPEs) have been investigated since the late 1960's for possible effects on the middle atmosphere. Solar protons from SPEs produce ionizations, dissociations, dissociative ionizations, and excitations in the middle atmosphere.
Douglass, Anne R. +2 more
core +1 more source
Are There Long-Term Benefits from Early Childhood Education in Low- and Middle-Income Countries?
, 2018 M. Najeeb Shafiq +2 more
openalex +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Estimating the Middle Class in Pakistan [PDF]
The concept ‘middle class’ is one of the most commonly used terms in the social sciences, including economics, sociology and political science. Despite its frequent use there is, however, no consensus on what the term exactly implies and its meaning ...
Durr-e-Nayab
core
Experimental Study of Middle-term Training in Social Cognition in Preschoolers
, 2015 Marine Houssa, Nathalie Nader‐Grosbois
openalex +2 more sources