Results 151 to 160 of about 4,582,425 (343)

Physical Function in Middle-aged and Older Adults with Type 1 Diabetes: Long-term Follow-up of the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study [PDF]

open access: gold, 2022
Catherine L. Martin   +9 more
openalex   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Social Long Term Care Insurance and Redistribution [PDF]

open access: yes
We study the role of social long term care (LTC) insurance when income taxation and private insurance markets are imperfect. Policy instruments include public provision of LTC as well as a subsidy on private insurance. The subsidy scheme may be linear or
Helmuth Cremer, Pierre Pestieau
core  

Sex differences in long-term effects of collagen-induced arthritis in middle-aged mice [PDF]

open access: gold, 2023
Bernhard Maximilian Schuh   +12 more
openalex   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Middle-Term Evolution of Efficiency in Permeable Pavements: A Real Case Study in a Mediterranean climate. [PDF]

open access: yesInt J Environ Res Public Health, 2020
Rodríguez-Rojas MI   +3 more
europepmc   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Depressive Symptoms in Middle Age and the Development of Later‐Life Functional Limitations: The Long‐Term Effect of Depressive Symptoms

open access: green, 2010
Kenneth E. Covinsky   +5 more
openalex   +2 more sources

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