Results 141 to 150 of about 2,329,754 (320)

Counterbalancing O‐GlcNAcylation and STAT3 Phosphorylation in Ventral Tegmental Area Dopaminergic Neurons Mediates Behavioral Adaptations to Acute Restraint Stress

open access: yesAdvanced Science, EarlyView.
Acute restraint stress enhances STAT3Ser727 phosphorylation in dopaminergic neurons in mice. This modification promotes the upregulation of GABBR2 and GABRB3, reduces neuronal activity, and contributes to anxiety‐like behavior and diminished reward‐seeking following stress exposure.
Mingshuo Shao   +10 more
wiley   +1 more source

Oxytocin Reduces Subjective Fear in Naturalistic Social Contexts via Enhancing Top‐Down Middle Cingulate Amygdala Regulation and Brain‐Wide Fear Representations

open access: yesAdvanced Science, EarlyView.
This double‐blind, placebo‐controlled study demonstrates that intranasal oxytocin reduces subjective fear in immersive, naturalistic social (but not non‐social) contexts. Concomitant fMRI reveals that oxytocin enhances middle cingulate activity and amygdala connectivity while it modulates network‐level connectivity and attenuates reactivity of a brain ...
Kun Fu   +17 more
wiley   +1 more source

Toward a New Distance to the Active Galaxy NGC 4258: II. Centripetal Accelerations and Investigation of Spiral Structure

open access: yes, 2007
We report measurements of centripetal accelerations of maser spectral components of NGC 4258 for 51 epochs spanning 1994 to 2004. This is the second paper of a series, in which the goal is determination of a new geometric maser distance to NGC 4258 ...
A. L. Argon   +8 more
core   +1 more source

Neutrophil Mobilization Triggers Microglial Functional Change to Exacerbate Cerebral Ischemia‐Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
These study underscores the pivotal role of neutrophil‐derived myeloid‐related protein 14 (MRP14) in the pathophysiology of acute ischemic stroke (AIS). MRP14 not only disrupts mitochondrial function, thereby inhibiting microglial phagocytosis of neutrophils, but also activates microglial pyroptosis, exacerbating neuroinflammation following AIS ...
Huijuan Jin   +10 more
wiley   +1 more source

Treatment of Midline Deviation with Miniscrews: A Case Report

open access: yesTurkish Journal of Orthodontics, 2017
A 15-year-old female presented with the chief complaint of crowding. Extraoral examination revealed little facial asymmetry, which was related with mandibular deviation caused by constriction of the maxilla.
Hasan Camcı, Cenk Doruk, Baran Talay
doaj   +1 more source

Observational Evidence for Massive Black Holes in the Centers of Active Galaxies

open access: yes, 2000
Naturally occurring water vapor maser emission at 1.35 cm wavelength provides an accurate probe for the study of accretion disks around highly compact objects, thought to be black holes, in the centers of active galaxies.
A. D. Haschick   +63 more
core   +2 more sources

Activation of Spinal Astrocyte α2A Adrenoceptors Protects Against Sepsis‐Induced Heart Injury Through Inhibition of GABAergic Neuronal Necroptosis

open access: yesAdvanced Science, EarlyView.
The study in this paper found that activating the α2A receptors of astrocytes in the thoracic spinal cord can reduce the release of inflammatory factors, thereby decreasing the necroptosis of GABAergic neurons and consequently alleviating myocardial injury caused by sepsis.
Ruilin He   +9 more
wiley   +1 more source

An ancestral axial twist explains the contralateral forebrain and the optic chiasm in vertebrates

open access: yes, 2014
Among the best-known facts of the brain are the contralateral visual, auditory, sensational, and motor mappings in the forebrain. How and why did these evolve?
de Lussanet, Marc H. E., Osse, Jan W. M.
core   +1 more source

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