Results 191 to 200 of about 94,665 (318)

A Sirtuin‐1‐Targeted Gene‐Activating Tetrahedral DNA Attenuates Bladder Fibrosis by Restoring Mitophagy in Fibroblasts via the SIRT1‐FOXO3‐BNIP3 Axis

Advanced Science, EarlyView.
The SIRT1‐targeted saRNA‐delivering tetrahedral DNA (TSA) treatment effectively upregulates SIRT1 expression, which subsequently promotes FOXO3A deacetylation. This deacetylation event relieves FOXO3A's transcriptional repression on the BNIP3 gene, thereby initiating PINK1‐PARKIN‐dependent mitophagy.
Wei Wang, Ran Yan, Lede Lin, Lei Xiang, Xiaozhi Xia, Liao Peng, Xiaoshuai Gao, Jiawei Chen, Yang Xiong, Liang Zhou, Yunfeng Lin   +10 more
wiley   +1 more source

Management of Dento-Maxillary Disharmony in Angle Class I Malocclusion with Anterior Crowding, Midline Shifting, and Deep Bite: A Case Report

, 2019
Staclyn Ongelina, Ida Bagus Narmada
openalex   +2 more sources

ROS‐Responsive Wedelolactone Hydrogel Promotes Intervertebral Disc Repair by Disrupting the NF‐κB–LCN2 Inflammatory Feedback Loop

Advanced Science, EarlyView.
A mechanically robust, ROS‐responsive hydrogel is engineered to treat intervertebral disc degeneration by targeting the NF‐κB–LCN2 inflammatory feedback loop. By delivering wedelolactone specifically within oxidative niches, this system disrupts macrophage–disc cell crosstalk.
Zimei Wu, Yan Xu, Lang Qin, Zemin Ling, Yingjie Mai, Xiong Tian Guo, Jiajia Chen, Leping Yan, Lin Wang, Liming Bian, Fuxin Wei   +10 more
wiley   +1 more source

A Universal Metal–Flavonoid Coating Strategy: Engineering Biomaterials for Diabetic Bone Regeneration

Advanced Science, EarlyView.
Construction of metal–flavonoid functionalized coatings on conventional bone repair materials. A one‐pot method is used to directly construct multifunctional metal–flavonoid coatings on the surface of traditional bone repair materials by selecting metal ions with osteogenic/angiogenic properties and flavonoids with reactive oxygen species scavenging ...
Chen Yang, Chenle Dong, Lefeng Su, Zhiqiang Liu, Lingyi Hu, Qishu Jin, Hao Chen, Chunlong Zhang, Yihao Wu, Jiang Chang, Zhaowenbin Zhang, Jiandong Yuan   +11 more
wiley   +1 more source

Deep learning-based prediction of mortality using brain midline shift and clinical information. [PDF]

Heliyon
Wu AR, Hsieh SY, Chou HH, Lai CS, Hung JY, Wang B, Tsai YS.   +6 more
europepmc   +1 more source

A nomogram for estimating intracranial pressure using acute subdural hematoma thickness and midline shift. [PDF]

Sci Rep, 2020
Liao CC, Liao HC, Lai F, Xiao F.
europepmc   +1 more source

Introduction to Wilderness Medicine - A Medical School Elective [PDF]

, 2020
Pittman, Mark, Slone, Trevor, Wilson, Matthew   +2 more
core  

Dento-maxillary disharmony class I malocclusion with severe crowding, crooked canine, midline shifting and lip incompetence management: A case report

Ida Bagus Narmada, Chitra Martalia, Intan VD. Hariati, Alvita Wibowo, Fenella Andrata   +4 more
openalex   +2 more sources

Revising Fascial Anatomy With a Focus on the Fusion Fascia in Mesenteric Gastrointestinal Cancer Surgery

Annals of Gastroenterological Surgery, EarlyView.
This review critically reassesses our prior hypothesis and proposes a revised anatomical model of the fusion fascia that is broadly applicable to GI cancer surgeries grounded in the principles of mesenteric resection. Our synthesis suggests that the fusion fascia is neither a dense connective tissue membrane nor a remnant of mesothelial fusion, but ...
Hisashi Shinohara, Yasunori Kurahashi, Jun Watanabe, Yuichi Nagakawa, Tatsuro Nakamura, Eiichiro Nakao, Yudai Hojo, Shugo Kohno, Motoki Murakami, Yoshinori Ishida   +9 more
wiley   +1 more source

Comparison of midline shift and ventricular size measured by transcranial ultrasound and non-contrast computed tomography in patients with acute subdural hemorrhage undergoing decompressive craniectomy: A prospective observational study. [PDF]

Surg Neurol Int
Gunasekaran A, Joy JJ, Ramadurai R, Chinnarasan V, Swaminathan S, Rajasekar G, Nagarajan K, Bidkar PU.   +7 more
europepmc   +1 more source