Results 51 to 60 of about 276,855 (304)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

THE COMPREHENSIVE MIDWIFERY CARE WITH NY. R IN DEPENDENT MIDWIFERY PRACTICE NURIL'S SIDOARJO

Indonesian Midwifery and Health Sciences Journal
Background: The maternal mortality rate in Indonesia in 2022 will be 189 / 100 thousand live births. This figure is still high when compared to the MMR target in 2024, namely 183 / 100 thousand live births.
Lidya Agustin Tjondro, Nurul Azizah
doaj   +1 more source

Correction to: Effect of Motivational Interviewing, Dietary Advice, and Physical Activity on Fetal-Neonatal Outcome in Pregnant Women with Metabolic Syndrome: A Randomized Controlled Trial

Journal of Mazandaran University of Medical Sciences, 2022
Correction to: Effect of Motivational Interviewing, Dietary Advice, and Physical Activity on Fetal-Neonatal Outcome in Pregnant Women with Metabolic Syndrome: A Randomized Controlled Trial Farideh Mohsenzadeh-ledari1,  Zahra Motaghi2,  Ziba Taghizadeh3,
Farideh Mohsenzadeh-ledari, Zahra Motaghi, Ziba Taghizadeh, Afsaneh Keramat, Ali Najafi, Mahmood Moosazadeh, Shahla Yazdani   +6 more
doaj  

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Midwifery Basics: Assessing students [PDF]

, 2015
Midwifery Basics: Mentorship 4 Mentorship: is the fourteenth series of ‘Midwifery basics’ targeted at practising midwives. It aims to provide information to raise awareness of the impact of the work of midwives on student learning and ultimately on ...
Marshall, Joyce, Parkin, Julie
core  

Exchanging ideas and good practice globally: reciprocal learning in the context of a twinning project [PDF]

, 2020
Between August and November 2019, I had the pleasure of making two trips to Bangladesh to support the Royal College of Midwives’ (RCM) twinning project with the Bangladesh Midwifery Society (BMS).
Kay, L.
core   +1 more source

Working together to implement a Pre-Qualifying Skills Passport in Wales: Report of a pilot project [PDF]

, 2016
Midwives are required to undertake a wide range of hands-on skills. Immediately upon qualification, they will be expected to use these skills safely and effectively as part of their practice.
Biggs J, Darra S, Dougherty L, Nursing and Midwifery Council, Nursing and Midwifery Council, Nursing and Midwifery Council, Nursing and Midwifery Council, Nursing and Midwifery Council, Nursing and Midwifery Council, Quality Assurance Agency for Higher Education, Vygotsky LS   +10 more
core   +2 more sources

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Exploring the conceptualization of strengthening the quality of midwifery education: A constructivist grounded theory study

International Journal of Africa Nursing Sciences
Background:  Strengthening the quality of midwifery education to international standards is necessary to prepare the midwifery workforce that can improve poor maternal and neonatal health. Unfortunately, Nigeria, with 1 047 deaths per 100 000 live births,
Waleola Bukola Ige, Winnie Baphumelele Ngcobo   +1 more
doaj   +1 more source