Results 41 to 50 of about 20,905 (195)
ABSTRACT Within corporate social responsibility (CSR) and environmental, social, and governance (ESG), there is a gap. This paper aims to fill that gap by building on a previous empirical study. It introduces the Land Governance Materiality Framework (LGMF), which redefines land governance as a critical governance skill that impacts ESG performance ...
Ifedayo Grace Malachi, Reza Eslamipoor
wiley +1 more source
Stability and Heat Input Controllability of Two Different Modulations for Double-Pulse MIG Welding
Aluminum alloy welding frequently experiences difficulties such as heat input control, poor weld formation, and susceptibility to pore generation. We compared the use of two different modulations for double-pulse metal inert gas (MIG) welding to reduce ...
Jiaxiang Xue +5 more
doaj +1 more source
Subclinical Cerebral Lesions in Migraine: A Proof-of-Concept Study on Platelet Aggregation. [PDF]
We assessed platelet aggregation in patients with migraine (n = 34) with or without cerebral white‐matter lesions (WMLs) versus matched controls (n = 34), with WMLs volume quantified by MRI (mm3). Aggregation to ADP, collagen, epinephrine, and arachidonic acid was measured; epinephrine‐induced aggregation at 1.25–2.5 μM was overall lower in migraine ...
Maestrini I +10 more
europepmc +2 more sources
Fluorinated Iminosugar Glycomimetics: Synthesis and Activity as GCase Ligands
DAST‐mediated deoxyfluorination of suitably functionalized piperidines provided regio‐ and stereoselective access to fluorinated piperidine and pyrrolidine glycomimetics, the latter arising from an unusual ring‐contraction process. Fluorination generally enhanced β‐glucocerebrosidase (GCase) inhibitory potency, but lost PC activity toward L444P/L444P ...
Francesca Mangiavacchi +9 more
wiley +1 more source
Amelioration of hypercholesterolemia by an EGFR tyrosine kinase inhibitor in mice with liver-specific knockout of Mig-6. [PDF]
Mitogen-inducible gene 6 (Mig-6) is a negative feedback inhibitor of epidermal growth factor receptor (EGFR) signaling. We previously found that Mig-6 plays a critical role in the regulation of cholesterol homeostasis and in bile acid synthesis.
Jun Choul Lee +10 more
doaj +1 more source
The Endothelial CXCR Family in Vascular Health and Disease
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu +4 more
wiley +1 more source
Abstract The term, minimally- or micro-invasive glaucoma surgery (MIGS), has entered common ophthalmic parlance and is playing an increasing role in the management of glaucoma patients. In common, the devices and procedures referred to are safer, less tissue invasive and associated with faster recovery than traditional filtering surgery, such
Jing Wang, Keith Barton
openaire +1 more source
An immunosuppressed 40‐year‐old man developed rapidly progressive polymicrobial pneumonia caused by Pneumocystis jirovecii and carbapenem‐resistant Klebsiella pneumoniae. Three metagenomic next‐generation sequencing (mNGS) and targeted next‐generation sequencing (tNGS) workflows with different assay designs and technical parameters consistently ...
Mengxia Wang, Jielun Wen, Liyue Sun
wiley +1 more source
Mig‐6 could inhibit cell proliferation and induce apoptosis in esophageal squamous cell carcinoma
Background To investigate the expression and biological functions of mitogen‐induced gene 6 (Mig‐6) in esophageal squamous cell carcinoma (ESCC). Methods The expression of Mig‐6 in ESCC tissues and normal esophageal epithelial tissues were measured by ...
Yuantao Cui +6 more
doaj +1 more source
Evolving Sacrocolpopexy Technique Trends
ABSTRACT Introduction Sacrocolpopexy (SCP) is widely considered the gold standard procedure for repairing apical and multi‐compartment prolapse. Despite its long‐standing and widespread use, significant technical variations persist, yet these differences have not been well‐characterized or linked to surgical outcomes.
Christina Sze +8 more
wiley +1 more source

