Results 71 to 80 of about 124,603 (293)
Serotonergic Modulators in Alzheimer's Disease: A Hope in the Hopeless Condition
Chemistry &Biodiversity, EarlyView.ABSTRACT Alzheimer's disease (AD) is the main cause of dementia worldwide. AD is a progressive brain neurodegenerative disease due to genetic and environmental factors that induce a progressive accumulation of intracellular hyperphosphorylated tau protein and extracellular amyloid protein (Aβ).
Najlaa Hamed Almohmadi +7 more
wiley +1 more source
eNeurologicalSci, 2022 Migraine is prevalent, disabling, and peaks during people's peak productive years. The impact of migraine on people's professional lives, work productivity, and interpersonal relationships at work eventually affects everyone, has a significant ...
Olivia Begasse de Dhaem, Fumihiko Sakai
doaj
Catheterization and Cardiovascular Interventions, EarlyView.ABSTRACT The patent foramen ovale (PFO), present in 25% of the population, can cause paradoxical embolism and stroke. Transcatheter PFO closure is the gold standard for recurrent embolism with significant inter‐atrial shunting, with recent trials confirming its superiority in reducing ischemic stroke recurrence over medical therapy.
Eirini Beneki +13 more
wiley +1 more source
NSAIDS AS MODULATORS OF CATION CHANNELS: FENAMATES REPURPOSING IN CHANNELOPATHIES
ChemMedChem, Accepted Article.Cationic ion channels are transmembrane proteins that regulate the flux of cations (potassium, sodium, and calcium) across cell membrane, playing a pivotal role in many cellular functions. Disruptions of their activity can lead to the so‐called genetic or acquired channelopathies, a heterogeneous group of diseases that affect multiple human systems ...
Paola Laghetti +4 more
wiley +1 more source
Clinical Pharmacology in Drug Development, EarlyView.Abstract Clascoterone is an androgen receptor inhibitor approved for the treatment of acne vulgaris in patients 12 years of age and older. Here, we report results of 5 phase 1 studies that assessed the pharmacokinetics (PK), safety, and skin irritation and sensitization potential of clascoterone cream 1% in healthy participants and patients with acne ...
Andrea Francesco Daniele Di Stefano +8 more
wiley +1 more source
Global assessment of migraine severity measure: preliminary evidence of construct validity
BMC Neurology, 2019 Background In persons with migraine, severity of migraine is an important determinant of several health outcomes (e.g., patient quality of life and health care resource utilization).
Tolulope T. Sajobi +6 more
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Continuing medical education in epileptology: The Level 1‐2‐3 experience of the ILAE academy
Epileptic Disorders, EarlyView.Abstract The International League Against Epilepsy (ILAE) Academy is the world's eminent e‐learning campus for epileptology. Its modular teaching content was developed to cover all competencies and learning objectives specified in the ILAE's curriculum for epileptology.
Ingmar Blümcke +78 more
wiley +1 more source
Ueber die operative Radical-Behandlung bestimmter Formen von Migraine, Asthma, Heufieber sowie zahlreicher verwandter Erscheinungen. Erfahrungen auf dem Gebiete der Nasenkrankheiten. Wiesbaden 1884 [PDF]
, 1884 Wilhelm Hack
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Epileptic Disorders, EarlyView.Abstract The accurate interpretation of scalp EEG remains an instrumental diagnostic component of epilepsy care. Knowledge of what constitutes normal EEG findings, non‐epileptiform abnormalities, and epileptiform patterns—both ictal and interictal—is essential for appropriate patient management.
Juan Luis Alcala‐Zermeno +9 more
wiley +1 more source
THE RELATION BETWEEN TRIGEMINAL NEURALGIAS AND MIGRAINE [PDF]
, 1900 JAMES J. PUTNAM
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