Results 111 to 120 of about 54,667 (268)

Integrated Clinical Trial and Molecular Profiling Reveals Immune Drivers of Chronic Hand Eczema

Allergy, EarlyView.
This study performed an unbiased molecular profiling of CHE patients across diverse etiologies to identify shared pathogenic drivers and evaluate the impact of IL‐4Rα blockade via dupilumab over 16 weeks. CHE shows a mixed immune signature involving type 1, 2, and 3 pathways with features of atopic dermatitis and psoriasis.
Perrine Gery, Rüçhan Ekren, Emilie Bérard, Aurélie Du‐Thanh, Hugo Rimet, Fatma Jendoubi, Vanina Lenief, Nadia Raison‐Peyron, Amel Bouznad, Maria P. Konstantinou, Jonathan Rioual, Lilian Basso, Juliette Mouiren, Manon Boussier, Brigitte Milpied, Cristina Bulai Livideanu, Louise Jaulent, Florence Hacard, Marine A. Lefevre, Audrey Nosbaum, Julien Seneschal, Marc Vocanson, Carle Paul, Nicolas Gaudenzio, Marie Tauber, on behalf of the French Atopic Dermatitis Network from de GREAT Research group   +25 more
wiley   +1 more source

Introducing self‐sampling for cervical cancer screening: A regional implementation study in Pirkanmaa, Finland

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
In this pilot study, HPV self‐sampling reached a 1.9% uptake among screening non‐attenders. Participants found the method acceptable, although overall screening coverage did not increase during the first implementation year. Abstract Introduction HPV primary testing is the preferred method for cervical cancer screening worldwide and enables vaginal ...
Saara Kyllönen, Satu Saloranta, Saara Kares, Anu Mustila, Karolina Louvanto   +4 more
wiley   +1 more source

Fania (Fanny) Kaplan and the attempted assassination of Vladimir Lenin: Ophthalmologic considerations

Acta Ophthalmologica, EarlyView.
Abstract Purpose Fania (Fanny) Kaplan (1890–1918), who was reportedly visually impaired, confessed to the attempted assassination of Soviet leader Vladimir Lenin (1870–1924) in 1918 by shooting him with a pistol. The precise nature of her visual loss is unknown and raises doubts about whether she had sufficient visual function to perform the act ...
Stephen G. Schwartz, Christopher T. Leffler, Peter M. Allen, Andrzej Grzybowski   +3 more
wiley   +1 more source

Multifactorial Nature of Childhood Stroke Presents a Major Challenge for Diagnosis and Management: A Population‐Based Study From Southern Finland

Acta Paediatrica, EarlyView.
ABSTRACT Aim Childhood ischemic stroke is rare but causes substantial long‐term morbidity, and its heterogeneous aetiology complicates timely diagnosis and management. Methods We conducted a retrospective population‐based observational study using hospital data and chart review to describe diagnostics, treatment and outcomes of ischemic stroke in ...
Jussi V. Leinonen, Samu Kurki, Siina Pamilo, Juho Immonen, Juha Knuuttila, Matti Hero, Mia Westerholm‐Ormio, Pirjo Isohanni, Miika Koskinen   +8 more
wiley   +1 more source

Screen Time Exposure and Children's and Adolescents' Health. A Position Paper from the European Academy of Paediatrics (EAP) and European Confederation of Primary Care Paediatricians (ECPCP)

Acta Paediatrica, EarlyView.
ABSTRACT Aim This position paper aims to synthesize current evidence on the effects of screen exposure on children's and adolescents' physical, mental and social health, critically review existing international and European guidelines, and propose coordinated, harmonized and age‐appropriate recommendations for policymakers, paediatric societies ...
Lorenza Onorati, Grigorios Papantoniou, Berthold Koletzko, Artur Mazur, Dominique Kyriaki Karafyllidou, Eugenio Baraldi, Laura Reali   +6 more
wiley   +1 more source

Genetic migraine disorders and the response to calcitonin gene-related peptide antagonist treatment. [PDF]

Headache
Kuczynski AM, Kingston WS.
europepmc   +1 more source

Meta‐Analysis: Chronic Gastrointestinal Symptoms and Comorbidities in Hypermobile Ehlers–Danlos Syndrome and Hypermobility Spectrum Disorders

Alimentary Pharmacology &Therapeutics, EarlyView.
This meta‐analysis reveals that a significant proportion of patients with hEDS/HSD experience gastrointestinal symptoms. The most prevalent symptoms include heartburn, abdominal pain, constipation, and nausea. There is a notable overlap of hEDS/HSD with chronic fatigue, DGBI, GERD, migraine, and orthostatic intolerance.
Dmitrii Kulin, Gerald Holtmann, Thomas Fairlie, Kyle Staller, Samuel Nurko, Laurie Keefer, Douglas A. Drossman, Michael P. Jones, Qasim Aziz, Ayesha Shah   +9 more
wiley   +1 more source

Decoding migraine disorders: parathyroid hormone-related peptide receptors as key genetic drivers. [PDF]

Brain Commun
Dias A, Ferreira M, Santos M, Sousa A, Oliveira C, Alves-Ferreira M, Lemos C.   +6 more
europepmc   +1 more source

Self‐Reported Health Problems of Birthing Persons During the First and Second Postpartum Years: Scope and Correlates

Birth, EarlyView.
ABSTRACT Background Postpartum health‐related problems are diverse, and some may extend beyond the first postpartum year. The purpose of this study was to describe women's postpartum health problems in the first and second postpartum years. Methods We analyzed data from an online survey (N = 427) conducted in 2024.
Sudhathai Sirithepmontree, Lina Palomares, Lorraine O. Walker   +2 more
wiley   +1 more source

Gold‐standard evidence and best practice guidance for menstrual cycle‐informed clinical care: An overview for clinicians

British Journal of Clinical Psychology, EarlyView.
Abstract Objectives To synthesize current evidence and provide clinically actionable recommendations for integrating menstrual cycle‐related processes—particularly hormone sensitivity, Premenstrual Dysphoric Disorder (PMDD) and Premenstrual Exacerbation (PME)—into psychological assessment, formulation and treatment.
Ellen R. Lambert, Louise N. Nolan, Katja M. Schmalenberger   +2 more
wiley   +1 more source