Results 131 to 140 of about 54,667 (268)

Rosemary metabolite carnosic acid opens Kv1.1 via its voltage sensor and corrects Kv1.1‐linked episodic ataxia in mice

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Episodic ataxia type 1 (EA1) is an autosomal dominant neurological disorder caused primarily by loss‐of‐function mutations in the voltage‐gated potassium channel Kv1.1 (KCNA1). Small molecules that restore Kv1.1 activity hold promise as targeted therapies for EA1, yet current pharmacological strategies remain limited ...
Rían W. Manville   +6 more
wiley   +1 more source

Targeting peroxynitrite production in a model of persistent temporomandibular disorder comorbid with migraine

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose The persistence of temporomandibular disorders (TMDs), particularly myogenous, in a person with migraine can lead to exacerbated clinical outcomes and limited response to treatment. The pro‐nociceptive reactive nitroxidative species, peroxynitrite, is involved in migraine mechanisms, but little is known of its role in this ...
Simon Akerman   +4 more
wiley   +1 more source

Caffeine and Headache: Exploring the Multifaceted Relationship. [PDF]

open access: yesBrain Behav
Hussein M   +6 more
europepmc   +1 more source

Static Otolith Signals Reflect Clinical Course in Acute Vestibular Neuritis

open access: yesClinical Otolaryngology, EarlyView.
ABSTRACT Objectives To investigate how static and dynamic utricular functions differentially correlate with dizziness symptoms and quality of life (QoL) recovery in patients with acute vestibular neuritis (VN). Design Prospective observational study with 1‐week and 1‐month follow‐up assessments. Setting Tertiary referral centre. Participants Twenty‐six
Seo‐Young Choi   +3 more
wiley   +1 more source

Nocturnal Hypoxemia Burden Correlates With Vestibular Dysfunction in Obstructive Sleep Apnea

open access: yesClinical Otolaryngology, EarlyView.
ABSTRACT Introduction Obstructive sleep apnea (OSA) is a potential contributor to vestibular dysfunction, though specific correlating parameters remain unclear. This study aimed to determine whether hypoxemia severity indices correlate quantitatively with caloric slow‐phase eye velocity (SPV), a marker of vestibular function. Methods In a retrospective
Dachan Kim   +2 more
wiley   +1 more source

The prevalence of comorbid migraine in multiple sclerosis: do multiple sclerosis and migraine really coexist? [PDF]

open access: yesJ Oral Facial Pain Headache
Kępczyńska K   +6 more
europepmc   +1 more source

Migraine in mitochondrial disorders [PDF]

open access: yesGeneral Internal Medicine and Clinical Innovations, 2018
Josef Finsterer, Sinda Zarrouk-Mahjoub
openaire   +1 more source

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