Results 51 to 60 of about 97,313 (319)

Migraine Comorbidities

Life
Novel knowledge about the interrelationships and reciprocal effects of migraine and epilepsy, migraine and mood disorders, or migraine and irritable bowel syndrome has emerged in recent decades.
Dan Iulian Cuciureanu, Cătălina Elena Bistriceanu, Georgiana-Anca Vulpoi, Tudor Cuciureanu, Florina Antochi, Adina-Maria Roceanu   +5 more
doaj   +1 more source

The burden of headache disorders in the Eastern Mediterranean Region, 1990-2016: findings from the Global Burden of Disease study 2016

The Journal of Headache and Pain, 2019
Objectives Using the findings of the Global Burden of Disease Study (GBD), we report the burden of primary headache disorders in the Eastern Mediterranean Region (EMR) from 1990 to 2016. Methods We modelled headache disorders using DisMod-MR 2.1 Bayesian
Kia Vosoughi, Lars Jacob Stovner, Timothy J. Steiner, Maziar Moradi-Lakeh, Seyed-Mohammad Fereshtehnejad, Farshad Farzadfar, Pouria Heydarpour, Reza Malekzadeh, Mohsen Naghavi, Mohammad Ali Sahraian, Sadaf G. Sepanlou, Arash Tehrani-Banihashemi, Reza Majdzadeh, Valery L. Feigin, Theo Vos, Ali H. Mokdad, Christopher J. L. Murray   +16 more
doaj   +1 more source

Insights into the Dynamics and Binding Mechanisms of the Alkhumra Virus NS2B/NS3 Protease: A Molecular Dynamics Study

Advanced Theory and Simulations, EarlyView.
The ΔRMSF$\Delta {\rm RMSF}$ analysis reveals significant flexibility differences between free NS3 and the NS2B/NS3 complex, with notable deviations in specific regions. Key residues driving NS2B binding are identified, and the protonation state of catalytic serine affects oxyanion hole formation.
Jurica Novak, Shivananda Kandagalla, Ramesh Sistla   +2 more
wiley   +1 more source

Bidirectional two-sample Mendelian randomization analysis identifies causal associations between migraine and five psychiatric disorders

Frontiers in Neurology
BackgroundThe question of whether a correlation exists between migraine and five psychiatric disorders, including posttraumatic stress disorder (PTSD), major depressive disorder (MDD), anorexia nervosa (AN), bipolar disorder (BIP), and schizophrenia (SCZ)
Wen-Wei Li, Jia-Xin Zhang, Jia Wang, Ya-qing Chen, Sha Lai, Zhi-Kun Qiu   +5 more
doaj   +1 more source

The Lung Microbiome Modulates Pain‐Like Behavior Via the Lung–Brain Axis in a Nitroglycerin‐Induced Chronic Migraine Mouse Model

Advanced Science, EarlyView.
Intratracheal neomycin alters pulmonary microbiota, activating the vagus nerve via lung brain‐derived neurotrophic factor/tropomyosin receptor kinase B (BDNF/TrkB) pathway, further projecting to nucleus of solitary tract (NTS), then dorsal raphe nucleus (DRN), where activated serotoninergic neurons increase brain serotonin, alleviating migraine.
Biying Liu, Chengya Huang, Xin Li, Haonan Yu, Yuefeng Xia, Kun Liu, Xingji You, Jingxiang Wu   +7 more
wiley   +1 more source

Management of Migraine-Associated Vestibulocochlear Disorders

Audiology Research, 2023
Migraine is a chronic neurological disorder that frequently coexists with different vestibular and cochlear symptoms (sudden hearing loss, tinnitus, otalgia, aural fullness, hyperacusis, dizziness, imbalance, and vertigo) and disorders (recurrent benign ...
Kayla K. Umemoto, Karen Tawk, Najva Mazhari, Mehdi Abouzari, Hamid R. Djalilian   +4 more
doaj   +1 more source

Vestibular and cochlear dysfunction in aging: Two sides of the same coin?

World Journal of Otorhinolaryngology - Head and Neck Surgery, Volume 8, Issue 4, Page 308-314, December 2022., 2022
Abstract Objective Nonspecific complaints of hearing loss, vertigo, imbalance, and instability, without a defined etiology, are very prevalent in the elderly population, with a great impact on morbidity and mortality in this age group. The objectives of this study were to verify whether there is age‐related vestibular dysfunction and to test the ...
Cátia Azevedo, Sérgio Vilarinho, Ana Sousa Menezes, Fernando Milhazes Mar, Luís Dias   +4 more
wiley   +1 more source

The Migraine–Stroke Connection [PDF]

Journal of Stroke, 2016
Migraine and stroke are common neurovascular disorders which share underlying physiological processes. Increased risks of ischemic stroke, hemorrhagic stroke, and subclinical ischemic lesions have been consistently found in migraineurs.
Mi Ji Lee, Chungbin Lee, Chin-Sang Chung
doaj   +1 more source

Shared Patterns of Brain Functional Connectivity for the Comorbidity between Migraine and Insomnia

Biomedicines, 2021
Migraine is commonly comorbid with insomnia; both disorders are linked to functional disturbance of the default mode network (DMN). Evidence suggests that DMN could be segregated into multiple subnetworks with specific roles that underline different ...
Kun-Hsien Chou, Chen-Yuan Kuo, Chih-Sung Liang, Pei-Lin Lee, Chia-Kuang Tsai, Chia-Lin Tsai, Ming-Hao Huang, Yi-Chih Hsu, Guan-Yu Lin, Yu-Kai Lin, Ching-Po Lin, Fu-Chi Yang   +11 more
doaj   +1 more source

Elucidating the Molecular Landscape of Cystic Kidney Disease: Old Friends, New Friends and Some Surprises

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Cystic kidney diseases (CyKD) are a diverse group of disorders affecting more than 1 in 1000 individuals. Over 120 genes are implicated, primarily encoding components of the primary cilium, transcription factors, and morphogens. Prognosis varies greatly by molecular diagnosis. Causal variants are not identified in 10%–60% of individuals due to
Deborah Watson, Frank Mentch, Jonathan Billings, Kayleigh Ostberg, Michael E. March, Jennifer M. Kalish, Dong Li, India Cannon, Lisa M. Guay‐Woodford, Erum Hartung, Alanna Strong   +10 more
wiley   +1 more source