Results 41 to 50 of about 1,421,169 (298)

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau   +11 more
wiley   +1 more source

CSF Cytokine Network Organization Predicts Progression Independent of Relapse and MRI Activity in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Progression independent of relapse activity is a major determinant of long‐term disability in multiple sclerosis, but its immunopathologic basis remains incompletely understood. We investigated whether relapse‐independent progression in radiologically stable relapsing–remitting multiple sclerosis is associated with distinct ...
Antonio Bruno   +19 more
wiley   +1 more source

Prevalence of migraine among adults with mood disorders: a Saudi cross-sectional study

open access: yesBMC Psychiatry
Background Migraine is characterized by recurrent headaches and frequently coexists with depressive and bipolar disorders, exacerbating disability and complicating management. Data on this association in Saudi Arabia remain limited, however.
Ahmad H. Almadani   +11 more
doaj   +1 more source

Association between attention deficit hyperactivity disorder (ADHD) and migraine: a review of observational studies

open access: yesHeadache Medicine, 2023
Introduction Attention deficit hyperactivity disorder (ADHD) has been related to the presence of primary headaches. Among them, migraine presents a wide range of comorbidities shared with  ADHD, both from other psychiatric disorders and  somatic ...
Henry Martins Soares Fortes   +1 more
doaj   +1 more source

Investigation of Complement Activation and Cytokine Signatures in AQP4+ NMOSD, MOGAD, and MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Aquaporin‐4‐IgG seropositive neuromyelitis optica spectrum disorder (AQP4+ NMOSD), myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD), and multiple sclerosis (MS) are pathophysiologically distinct neuroinflammatory disorders. Complement activation is a major mechanism of injury in AQP4+ NMOSD, whereas its role in
Angeliki G. Filippatou   +23 more
wiley   +1 more source

Non-headache symptoms in migraine patients [version 1; referees: 2 approved]

open access: yesF1000Research, 2018
Migraine is one of the most common neurological disorders. In addition to severe headaches, non-headache symptoms associated with migraine attacks as well as co-morbid disorders frequently aggravate the disabling of migraine patients.
Ping-Kun Chen, Shuu-Jiun Wang
doaj   +1 more source

Comorbidities in patients with migraine in Japan: a cross-sectional study using data from National Health and Wellness Survey

open access: yesBMJ Open, 2022
Objectives This study aims to examine the association between migraine and various psychiatric and somatic comorbidities in Japan.Design Cross-sectional study using existing data of the 2017 Japan National Health and Wellness Survey (NHWS).Setting ...
Yirong Chen   +5 more
doaj   +1 more source

Population-based studies on the epidemiology of migraine and Parkinson's disease [PDF]

open access: yes, 2007
With epidemiologic analyses the effect of certain exposures on diseases can be studied in large population samples. Pharmacoepidemiology is a speciality which focuses on beneficial or harmful drug effects on the development of diseases.
Becker, Claudia
core   +1 more source

Juvenile Huntington Disease With Cerebellar‐Predominant Atrophy Identified by Genome Sequencing

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Juvenile Huntington disease accounts for a small fraction of Huntington disease cases and is driven by the largest trinucleotide repeat expansions. We describe a 6‐year‐old boy with progressive global regression, generalized dystonia, and epilepsy, in whom serial imaging showed striking cerebellar‐predominant atrophy with an initially normal ...
Enrique Gonzalez Saez‐Diez   +5 more
wiley   +1 more source

A narrative review on the burden of migraine: when the burden is the impact on people’s life

open access: yesThe Journal of Headache and Pain, 2019
Background The burden of headache disorders, and of migraine in particular, is multifaceted and fragmented. The aim of this narrative review is to provide a description the main topics underlying the concepts of burden and impact of migraine disorders ...
Matilde Leonardi, Alberto Raggi
doaj   +1 more source

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