Results 61 to 70 of about 97,313 (319)

Neurodegeneration in multiple sclerosis

WIREs Mechanisms of Disease, Volume 15, Issue 1, January/February 2023., 2023
Chronic demyelination results in impaired axon metabolism and function, ultimately leading to progressive neurological decline. Neuroprotective strategies aim to protect axons from inflammatory‐mediated destruction, thereby improving axonal integrity and clinical disability (Image created in BioRender.com).
Gabrielle M. Mey, Kedar R. Mahajan, Tara M. DeSilva   +2 more
wiley   +1 more source

Eating attitudes of migraine patients in Turkey: a prospective multi-center study

BMC Neurology
Background Migraine is a disease characterized by headache attacks. The disease is multifactorial in etiology and genetic and environmental factors play role in pathogenesis.
Ruhsen Ocal, Basak Karakurum-Goksel, Mert Van, Ozlem Coskun, Cihad Karaaslan, Serap Ucler, Figen Gokcay, Nese Celebisoy, Hadiye Sirin, Aysin Kisabay Ak, Aysegul Seyma Saritas, Tuba Cerrahoglu Sirin, Buse Rahime Hasirci Bayir, Esme Ekizoglu, Elif Kocasoy Orhan, Derya Bayram, Nermin Tanik, Sebnem Bicakci, Vesile Ozturk, Levent Ertugrul Inan, Kubra Mehel Metin, Yasemin Eren, Babur Dora, Emel Oguz-Akarsu, Necdet Karli, Emel Ur Celik, Arife Cimen Atalar, Rabia Gokcen Gozubatik Celik, Belgin Mutluay, Elif Ilgaz Aydinlar, Pinar Yalinay Dikmen, Sencer Semercioglu, Ufuk Emre, Osman Cagin Buldukoglu, Busra Er, Bekir Burak Kilboz, Seray Ibis, Sibgetullah Yagiz, Huzeyfe Koklu, Ibrahim Kamaci, Gulshan Aliyeva, Basak Elcin Ates, Muge Mercan Kara, Fatma Zehra Altunc, Ilgin Kaya, Cagla Sisman   +45 more
doaj   +1 more source

Linking a genetic defect in migraine to spreading depression in a computational model [PDF]

, 2014
Familial hemiplegic migraine (FHM) is a rare subtype of migraine with aura. A mutation causing FHM type 3 (FHM3) has been identified in SCN1A encoding the Nav1.1 Na$^+$ channel. This genetic defect affects the inactivation gate. While the Na$^+$ tail currents following voltage steps are consistent with both hyperexcitability and hypoexcitability, in ...
arxiv   +1 more source

Perspectives on rosacea patient characteristics and quality of life using baseline data from a phase 3 clinical study conducted in Japan

The Journal of Dermatology, Volume 49, Issue 12, Page 1221-1227, December 2022., 2022
Abstract There is a lack of contemporary data on rosacea originating in Japan. Using baseline data from a randomized, phase 3 study of 130 Japanese patients with rosacea treated with metronidazole gel (0.75%) or vehicle, the authors evaluated demographic and clinical characteristics, pretreatment quality of life, and exacerbating factors.
Kenshi Yamasaki, Yoshiki Miyachi
wiley   +1 more source

Primary headache disorders and neuro-ophthalmologic manifestations

Eye and Brain, 2012
Daniel P Schwartz, Matthew S RobbinsDepartment of Neurology, Montefiore Headache Center, Albert Einstein College of Medicine, Bronx, NY, USAAbstract: Headache is an extraordinarily common complaint presenting to medical practitioners in all arenas and ...
Schwartz DP, Robbins MS
doaj  

Signs of Cortical Inflammation in Migraine Measured with Quantitative Magnetic Resonance Imaging: A Registry for Migraine (REFORM) Study

Annals of Neurology, EarlyView.
Objective The involvement of cortical inflammation in migraine, particularly migraine with aura, has been a subject of considerable interest, but has proved challenging to demonstrate. We aimed to detect and characterize signs of cortical inflammation in adults with migraine using a novel, multimodal magnetic resonance imaging (MRI) technique.
Rune H. Christensen, Håkan Ashina, Haidar M. Al‐Khazali, Mario Ocampo‐Pineda, Reza Rahmanzadeh, Nouchine Hadjikhani, Cristina Granziera, Faisal Mohammad Amin, Messoud Ashina   +8 more
wiley   +1 more source

Obstetrical and neonatal complications in hereditary haemorrhagic telangiectasia: A retrospective study

BJOG: An International Journal of Obstetrics &Gynaecology, Volume 130, Issue 3, Page 303-311, February 2023., 2023
Abstract Objective To retrospectively describe a large series of pregnancies in women with hereditary haemorrhagic telangiectasia followed in our reference centre, plus neonatal outcomes, to better understand the risks of complications and to improve their prevention.
Laura Delagrange, Olivier Dupuis, Anne‐Emmanuelle Fargeton, Lorraine Bernard, Evelyne Decullier, Sophie Dupuis‐Girod   +5 more
wiley   +1 more source

Association between personality disorders and migraine. A narrative review

Journal of Education, Health and Sport
Introduction: Migraine is one of the most prevalent types of headache and is a subject of many clinical trials. There are various risk factors associated with migraine occurrence, from hormonal and genetic to environmental.
Ewa Olek, Oliwia Szewczyk, Karolina Czarnecka, Anna Korczak, Katarzyna Burda, Emilia Wójcik, Olga Łopacińska, Katarzyna Stańczyk, Aleksandra Korn, Justyna Jędrzejczyk   +9 more
doaj   +1 more source

Effectiveness of integrated education and relaxation program on migraine-related disability: a randomized controlled trial

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2023
Background Migraine is one of the most disabling disorders worldwide. Globally, in 2019, headache disorders were the cause of 46.6 million years of disability, with migraine accounting for 88.2% of these.
Sara Hisham, Ayat Manzour, Mohammed M. Fouad, Randa M. Amin, Hisham A. Hatata, Diaa Marzouk   +5 more
doaj   +1 more source

Distinct Alterations of Inflammatory Biomarkers in Cluster Headache: A Case Control Study

Annals of Neurology, EarlyView.
Objective Investigate the immune system's role in cluster headache by analyzing cytokines in people with cluster headache and headache‐free controls, and explore if certain cytokines could predict a specific phenotype. Methods We measured 45 cytokines in adult participants from the Danish Cluster Headache Biobank in a prospective case–control setup ...
Nunu Laura Timotheussen Lund, Connar Stanley James Westgate, Marie‐Louise Kulas Søborg, Agneta Henriette Snoer, Rigmor Højland Jensen, Thomas Folkman Hansen, Anja Sofie Petersen   +6 more
wiley   +1 more source