Results 111 to 120 of about 18,405 (235)

Investigating Bidirectional Causal Relationships Between Imaging‐Derived Brain Phenotypes and Sedative‐Hypnotic Use Disorder: A Mendelian Randomization Study

open access: yesAddiction Biology, Volume 31, Issue 6, June 2026.
Using bidirectional two‐sample Mendelian randomisation across 3935 brain imaging‐derived phenotypes, we causally linked specific neuroimaging features to sedative‐hypnotic use disorder (SHUD) susceptibility. Increased cortical thickness in temporal‐limbic regions and altered default mode network connectivity conferred risk, whereas larger brainstem ...
Liqin Lu   +6 more
wiley   +1 more source

Serial systemic immune inflammation indices: markers of acute migraine events or indicators of persistent inflammatory status?

open access: yesThe Journal of Headache and Pain
Background Migraine is the most common complex neurological disorder, affecting over a billion people worldwide. Neurogenic inflammation has long been recognized as a key factor in the pathophysiology of migraine though little research has been directed ...
Tissa Wijeratne   +8 more
doaj   +1 more source

Insights into Migraine with Aura

open access: yes
The migraine aura is one of the most fascinating and complex phenomena of clinical neurology and neuroscience. While the earliest known accounts of migraine with aura were provided by Hippocrates (Rose, Cephalalgia 15:1–3, 1995), the disorder continues ...
Hougaard, Anders   +1 more
core   +1 more source

Proposal for a Migraine Aura Complexity Score

open access: yes, 2019
Objectives: Currently, there is no scoring system for assessing the complexity of migraine aura. Our goal was to develop a Migraine Aura Complexity Score that synthesizes the quantity and quality of aura symptoms and to test its applicability in ...
Petrusic, Igor   +4 more
core   +1 more source

Cerebrospinal Fluid and Plasma Concentrations of Atogepant in Humans

open access: yesClinical and Translational Science, Volume 19, Issue 6, June 2026.
ABSTRACT The aim of this study was to determine the cerebrospinal fluid (CSF) to plasma concentration ratio of atogepant. Healthy adult participants (N = 28) were enrolled into this phase 1, open‐label study and received atogepant 60 mg once daily for 8 days. Steady‐state atogepant concentrations were determined from CSF samples collected on Day 6 at 2
Ramesh R. Boinpally, Joel M. Trugman
wiley   +1 more source

Migraine and Restless Legs Syndrome: A Meta‐Analysis

open access: yesJournal of Sleep Research, Volume 35, Issue 3, June 2026.
ABSTRACT Restless legs syndrome is a sensorimotor disorder of sleep/wake regulation that frequently coexists with migraine, affecting patients' quality of life. This study aimed to estimate the prevalence of restless legs syndrome in individuals with migraine and to explore the associated clinical, demographic and behavioural aspects.
Florindo d'Onofrio   +8 more
wiley   +1 more source

Visual cortex excitability in migraine with and without aura.

open access: yes, 2001
Objectives.—Previous research using transcranial magnetic stimulation has produced equivocal findings concerning thresholds for the generation of visual phosphenes in migraine with aura.
Palmer, Joanne E.   +9 more
core   +1 more source

Strategies for Treating Acute Migraines and Identifying Triggers. Literature review

open access: yesJournal of Education, Health and Sport
Introduction Migraine, a prevalent neurological disorder affecting a substantial portion of the global population, poses a significant burden on individuals' overall quality of life.
Zuzanna Kotowicz   +8 more
doaj   +1 more source

Temperamental characteristics in childhood migraine without aura: a multicenter study

open access: yes, 2013
Maria Esposito,1 Rosa Marotta,2 Beatrice Gallai,3 Lucia Parisi,4 Giuseppina Patriciello,1 Serena Marianna Lavano,2 Giovanni Mazzotta,5 Michele Roccella,4 Marco Carotenuto11Center for Childhood Headache, Clinic of Child and Adolescent Neuropsychiatry ...
Lavano SM   +8 more
core  

What does a migraine aura look like?—A systematic review

open access: yesThe Journal of Headache and Pain
Migraine with aura is a prevalent neurological disorder that affects up to 30% of individuals experiencing migraines. It presents as temporary neurological disturbances, primarily visual, but also includes sensory, speech, motor, and brainstem symptoms ...
Ľubica Joppeková   +10 more
doaj   +1 more source

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