Results 101 to 110 of about 1,506,509 (302)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Rape Crisis Centre 2002 statistics and financial summary.

open access: yes, 2003
I have audited the financial statements above and opposite in accordance with Auditing Standards. In my opinion, the financial statements give a true and fair view of the statement of the company's affairs at 31 st December 2002, and of its results ...
Rape Crisis Centre.
core  

The social thought of the Orthodox Church reflected in the documents of the Holy Pan-Orthodox Council of Crete (2016)

open access: yesHTS Teologiese Studies/Theological Studies, 2019
An important moment in the history of the Orthodox Church is despite the withdrawal of local churches like the Bulgarian, Russian, Georgian and Alexandrian ones and the fear of Serbian Church to take part in it, the Pan-Orthodox Council of Crete remains ...
Iuliu-Marius Morariu
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

A Brief History of the Migrant Mothers Project

open access: yes, 2019
The Migrant Mothers Project (MMP) is a collaborative research project led by Rupaleem Bhuyan at the University of Toronto in partnership with a network of service providers, legal advocates, community health workers, and grassroots women.
Migrant Mothers Project
core  

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Administrative guide : Kansas Migrant Education Program [1987]

open access: yes, 1987
Chapter 1 Introduction -- Chapter II Administration of Migrant Education Programs -- Chapter III Local School Migrant Projects -- Chapter IV The Application Process -- Federal ...
Kansas Migrant Education Program
core  

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Report to the Governor : Migrant Status Report : Fall 1986 [1986]

open access: yes, 1986
Migrant Status Report Fall, 1986 -- Report to the Governor -- Acknowledgements -- I. History -- II. Preliminary Report -- III. The Kansas State Migrant Coordinating Council -- A. General -- B. Current Activities and Accomplishments -- C. Current Problems
Kansas State Migrant Coordinating Council
core  

Models for countering the segregation of ethnoreligious immigrant areas in Denmark and Sweden

open access: yesBaltic Region
The article explores the immigration and integration strategies of Denmark and Sweden while assessing their efficacy. The two countries, sharing historical, cultural, social and economic similarities, face a common challenge: the formation of ...
Talalaeva E. Yu. , Pronina T. S.
doaj   +1 more source

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