Results 81 to 90 of about 1,506,509 (302)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Migrant Agricultural Ombudsman report [PDF]

open access: yes
Annual; Summarizes the migrant farm worker season and makes recommendations to improve the conditions of farm workers in Ohio.; Vol. for 2004- prepared by: Office of Workforce Development, Bureau of Tax Credit Services, Migrant & Seasonal Farm Workers ...
Migrant & Seasonal Farm Workers Program (Ohio)
core  

Migrant Crisis

open access: yes
AbstractThis chapter on refugee and asylum seeker narratives includes both fiction and nonfiction. Examining the migrant condition in relation to concepts such as gratitude, empathy, and dignity emerge as central, since they not only highlight the personal experiences of migrants but also place them in a wider societal and political context.
openaire   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Impact of the economic crisis on human mobility in Japan : a preliminary note

open access: yesBelgeo, 2011
The central aim of this paper is to explore the impact of the global economic crisis on different categories of human mobility, including migration and tourism, in Japan. The major findings can be summarized as follows.
Yoshitaka Ishikawa
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Financial Crisis Inquiry Commission

open access: yes, 2011
This website contains the research and final report for the Financial Crisis Inquiry Commission looking at the causes of the economic ...
United States. Financial Crisis Inquiry Commission.
core  

Javanese Leadership And Migrant Worker Repatriation: A Model For Transformative Crisis Response

open access: yesJournal of Political Issues
This journal article presents an in-depth analysis of the leadership approach exhibited by Retno Marsudi as Minister of Foreign Affairs of Indonesia, during the critical process of withdrawing Indonesian migrant workers from multiple countries in the ...
Setyasih Harini   +2 more
doaj   +1 more source

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