Results 71 to 80 of about 17,295 (308)
Teaching & Learning Inquiry: The ISSOTL JournalThis research assesses how interdisciplinary pedagogical interventions can prepare students to tackle complex problems, such as the refugee and migrant crisis.
Emily Wierszewski, Roni Kay O'Dell
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
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Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
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The Crisis Impact on the Labour Market [PDF]
The aim of this paper is to discuss the impact of the current global economic crisis on the labour market, including the risk that the recession will be followed by a jobless recovery that contributes to a lost generation of young people in the workforce.
Simona Valeria TOMA +1 more
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Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
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BMJ Paediatrics OpenIntroduction Latin America and the Caribbean (LAC) is one of the regions most affected by the climate crisis, which is connected to international migration through a complex nexus. During the last years, migratory flows on the continent have increasingly
Baltica Cabieses +2 more
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An institutional perspective on managing migrant workers in the North of England
, 2010 Despite advances made in our understanding of migrant worker issues, analysis of the literature reveals disconnections between the policy and practice of 'managed migration' across three fundamental levels of the state (e.g. public institutions at the EU,
Fitzgerald, Ian, Chan, Paul
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Visual representation of migrant crisis in Czech printed media [PDF]
, 2018 The Master's thesis 'Visual representation of migrant crisis in Czech printed media' examines how certain czech newspapers informed about migrant crisis. The first part of the thesis introduces the core theoretical concepts, that serve as a basis for the
Zitka, Lukáš
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
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Migrant Crisis in the Mediterranean from the Perspective of Realism Theory [PDF]
The Review of International AffairsThe Mediterranean migrant crisis, fueled by conflict, poverty and political instability in countries of origin, positions the Mediterranean as the deadliest sea in the world.
Slobodan M. Radojević
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