Results 41 to 50 of about 17,295 (308)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

The Dual Scope of the Refugee Crisis: Humanitarian Disaster or Terrorist Threat? [PDF]

open access: yesBezbednosni Dijalozi, 2019
The refugee crisis remains a top priority topic for discussion and solution on the international scene. The dilemma remains whether the mass migration happening from Africa and Asia to Europe is a humanitarian issue, security threat, economic burden, or
Leta Bardjieva MIOVSKA
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Religious elements of media reporting on migrants: A comparison of journalist and reader perspectives [PDF]

open access: yesSociološki Pregled
Given that media narratives about migrants are permeated with political, economic, and religious factors, the aim of this analysis is to identify and compare patterns in reporting on the migrant crisis with patterns in readers' comments.
Stamenković Ivana S.
doaj   +1 more source

Belarus/EU migrant crisis

open access: yes, 2021
Belarus has been accused of engineering a migrant crisis at its borders with the EU.
BUTCHARD, PATRICK; id_orcid   +3 more
core  

European Union’s stance on the Belarus-European Union border migrant crisis compared to the 2015-16 migrant crisis [PDF]

open access: yes, 2022
European Union has recently faced two migrant crises, 2015-16 migrant crisis in which estimated 1,4 million migrants made their way into Europe and the European Union-Belarus border crisis in which at least 40 000 migrants had tried tried crossing into ...
Kerge, Tanel
core  

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

EU integration in the (post)-migrant-crisis context: learning new integration modes? [PDF]

open access: yes, 2020
This article explores the integration of the European Union (EU) as an institution after the 2015-2016 migrant crisis. Qualitative data from elite interviews in Brussels and policy analysis, in the framework of a bigger project about the impact of the ...
Kilkey, M.   +5 more
core   +1 more source

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