Results 91 to 100 of about 6,283,030 (249)

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Migrant Camps students

, 1990
Students at a local migrant camp are posing with their class ...

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Learning through social spaces: migrant women and lifelong learning in post-colonial London [PDF]

, 2010
This article shows how migrant women engage in learning through social spaces. It argues that such spaces are little recognised, and that there are multiple ways in which migrant women construct and negotiate their informal learning through socialising ...
Jackson, Sue, Paul B. Wignall, Wang, Wei, Bond, David P.G., Lai, X, Jiang, Haishui, Mike Widdowson, Bond, DPG, Jiang, H, Lai, Xulong, Chunbo Yan, Yadong Sun, Yan, Chunbo, Wei Wang, David P.G. Bond, Wang, W, Yan, C, Ali, Jason R., Xulong Lai, Ali, JR, Jason R. Ali, Stéphanie Védrine, Wignall, Paul B., Haishui Jiang, Widdowson, M, Widdowson, Mike, Sun, Yadong, Védrine, Stéphanie, Védrine, S, Sun, Y, Wignall, PB   +30 more
core   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Negotiation and Agency of Migrant Students within Salafi Muslim Communities in Pekanbaru

Jurnal Dakwah Risalah
This article analyzes the negotiation practices and agency of Muslim migrant university students in Pekanbaru in response to Salafi power relations. Economic constraints drive many of these migrant students to reside in community-owned mosques, including
Dony Arung Triantoro, Yudhisti Indra Fz, Bifa Fanisa Basri   +2 more
doaj   +1 more source

U-Minnesota Migrant Project Newsletter. May 1996

, 1996
University-Migrant Project. (1996). U-Minnesota Migrant Project Newsletter. May 1996.
University-Migrant Project
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Exploring the learning experiences of migrant students in urban China [PDF]

, 2017
Due to globalization and market economy influences, substantive changes have occurred in Chinese education, producing inequalities between migrant and urban students.
Wenjue Chen
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Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

Challenges Faced by Migrant Students in Education: A Comprehensive Analysis of Legal, Psychological, and Economic Barriers

Qubahan Academic Journal
This study aims to explore the multifaceted challenges faced by migrant students in educational settings, focusing on legal, psychological, and economic barriers. The research employs a mixed-methods approach, combining quantitative and qualitative data
Khasanboy Abdusamatov, Dinara Babajanova, Dilshodjon Egamberdiev , Yunus Xodjiyev , Uktamjon Tukhtaev, Nodirbek Yusupov , Sitora Shoislomova   +6 more
doaj   +1 more source