Results 111 to 120 of about 192,825 (305)
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Humanities & Social Sciences CommunicationsThe educational spillovers of migrant children in receiving areas have drawn widespread attention in countries undergoing massive internal migration.
Xiaodong Zheng, Yanran Zhou
doaj +1 more source
Brown Eyes, Brown Mind: What We Learn From What We See
, 2013 My summer days aren’t spent in a house on the beach or travelling to different states or countries with my family or friends, forgetting about the worries of the rest of the year and wondering what could be better than life under the sun.
Novoa, Mauricio E.
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Blurred Borders: Trans-Boundary Impacts & Solutions in the San Diego-Tijuana Border Region [PDF]
, 2004 Over the years, the border has divided the people of San Diego County and Tijuana over language, culture, national security, public safety and a host of other cross-border issues ranging from human migration to the environment. For some, the 'us' versus '
Naoka Kada, Richard Kiy
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Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
InnoeducaThis work addresses the impact of a mobile application designed to improve the literacy skills of migrant students in Primary Education in Spain. Since the 1990s, Spain has experienced a significant increase in migrants, leading to an educational ...
Inmaculada Aznar Díaz +3 more
doaj +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Fearless (Saturday): Michael Hannum
, 2013 In celebration of Alumni Homecoming Weekend and Hispanic Heritage Week, we proudly feature Michael Hannum, member of the Class of 2011, for his fearless commitment to fighting for social justice issues and his continued involvement in serving the Adams ...
Hannum, Michael W.
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Student and School Indicators for Youth in California's Central Valley [PDF]
, 2002 Provides a statistical portrait of elementary, secondary, and postsecondary education in the Central Valley. Examines trends in school resources, course enrollment, and student achievement in the region, and compares to trends in the rest of the ...
Anne Danenberg +2 more
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University experiences in students migrants
Revista de Investigación en Psicología, 2017 In this work the field of interest focuses on the experiences of college students who migrate to study the atmosphere to the city of Cordoba and its relationship to study processes in the course of Psychology. The purpose is to analyze the experiences of migrant students and their relationship with the processes of setting, autonomy and organization ...
openaire +1 more source