Results 91 to 100 of about 705,445 (342)
Retired EU migrants, healthcare rights and European social citizenship [PDF]
, 2001 Drawing on a set of 210 qualitative interviews conducted in six European countries, this paper investigates the citizenship status and experiences of retired EU migrants at both national and European levels.
Dwyer, PJ
core +2 more sources
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
No. 08: International Migration and Urban Food Security in South African Cities [PDF]
, 2017 The drivers of food insecurity in rapidly growing urban areas of the Global South are receiving more research and policy attention, but the precise connections between urbanization, urban food security and migration are still largely unexplored.
Crush, Jonathan, Tawodzera, Godfrey
core +1 more source
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
The urban integration of refugee migrants in the light of the justice concept of Amartya Sen
Revista de Direito Econômico e Socioambiental, 2018 This article proposes an analysis of the current situation of refugee migrants and their relationship with countries that seek as a place of protection, from the perspective of urban integration in the light of Amartya Sen's ideas on justice and freedom.
Ligia Maria Silva Melo de Casimiro +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
À l’école du Nord. La scolarisation des enfants de migrants du Mezzogiorno dans les années 1960
Cahiers d’histoire, 2019 The family migration of people from South Italy to cities in the industrial triangle of northern Italy in the influences the schooling of children in a prejudicial way. The failures are numerous and school paths are shortened.
Anna Badino
doaj +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source