Results 21 to 30 of about 217,499 (311)
We analyze the migrant smuggling market where smugglers differ in their capacities to exploit their clients' labor in the destination. We show that when exploitation capacities are private information, the equilibrium may be characterized by adverse selection.
openaire +2 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
The Labour Market Mobility of Polish Migrants: A Comparative Study of Three Regions in South Wales, UK [PDF]
Since Polish migrants began entering the UK labour market in the post-accession period, there has been a significant amount of case study research focusing on the impact of this large migrant group on the UK economy.
Knight, Julie +2 more
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
The Corona Virus Disease-2019 (COVID-19) pandemic has influenced the lives of millions of people across the world and forced all the public health authorities to divert their attention towards the disease.
Saurabh Shrivastava, Prateek Shrivastava
doaj +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
EL “PAPER” COMO UN CAMPO DE BATALLA: CONVERSACIONES ACADÉMICAS DESLENGUADAS
Esta reflexión constituye una indagación, a cuatro manos y dos corazones, sobre la práctica de la escritura académica, las lógicas, contradicciones, presupuestos y posibilidades para el surgimiento de un pensamiento auroral, esto es, para el ...
María Fernanda Moscoso Rosero +1 more
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
How do the Romanians Experience the Process of Transnationalism? Canada and the UK Compared
The rapid improvement of technologies and communication has made it easier for migrants to maintain close links with their country of origin. Given the lack of empirical investigation on transnationalism, this comparative study argues that this process ...
Claudia Paraschivescu
doaj

