Results 41 to 50 of about 296,708 (302)

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

The remitting patterns of African migrants in the OECD [PDF]

open access: yes
Recorded remittances to Africa have grown dramatically over the past decade. Yet data limitations still mean relatively little is known about which migrants remit, how much they remit, and how their remitting behavior varies with gender, education ...
Morten, Melanie   +2 more
core   +2 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

PTSD and complex PTSD manifestations in Sub-Saharan Africa: A systematic review of qualitative literature

open access: yesSSM - Mental Health
Complex post-traumatic stress disorder (CPTSD) was introduced in the ICD-11 as a new diagnosis and was framed in accordance with WHO guidelines of clinical utility and cross-cultural applicability.
Marion Bovey   +3 more
doaj   +1 more source

Reconsidering the migrant letter: from the experience of migrants to the language of migrants [PDF]

open access: yesThe History of the Family, 2016
AbstractFollowing a century of scholarly attention, the migrant letter, whether written by family members, lovers, friends, or others, is a document that continues to attract the attention of scholars and general readers. Over time, the study of migrant letters has developed in myriad directions.
Marcelo J. Borges, Sonia Cancian
openaire   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Entre Deux Drapeaux: Les ouvriers capverdiens au Portugal pendant la période revolutionnaire (1974-1976)

open access: yesCadernos de Estudos Africanos, 2011
Marqués par un climat de décolonisation, les mois qui suivirent la Révolution des Oeillets (25 avril 1974) constituèrent une période d’incertitude pour les Capverdiens vivant et travaillant en tant qu’ouvriers au Portugal.
Antoine Acker
doaj   +1 more source

Multiple exclusion homelessness amongst migrants in the UK [PDF]

open access: yes, 2012
This article examines the experience of ‘multiple exclusion homelessness’ (MEH) amongst migrants to the UK. Homelessness and destitution amongst migrants has become a matter of growing concern in many European countries in recent years, particularly with
Johnsen, Sarah   +2 more
core  

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