By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Boko Haram and the Geopolitics of Forced Migration in Nigeria
Journal of International Studies, 2018 Migration is currently perceived as an epitome of globalization and a measuring gauge of global geopolitical mobility. In recent years, Nigeria has been faced with a series of migratory crises such as insurgency and conflict, forcing large numbers of ...
Sadiq Mukhtar +3 more
doaj +3 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
How do the Romanians Experience the Process of Transnationalism? Canada and the UK Compared
Sociologie Românească, 2011 The rapid improvement of technologies and communication has made it easier for migrants to maintain close links with their country of origin. Given the lack of empirical investigation on transnationalism, this comparative study argues that this process ...
Claudia Paraschivescu
doaj
Becoming local citizens: Senegalese migrants and agrarian clientelism in the Gambia [PDF]
, 2012 Drawing on ethnographic research with Senegalese female migrants in Brikama, The Gambia this article examines local citizenship and agrarian clientelism.
Kea, Pamela
core +2 more sources
Broken lines of Il/Legality and the reproduction of state sovereignty: the impact of visa policies on immigrants to Turkey from Bulgaria [PDF]
, 2009 After the granting of citizenship to the 300,000 Turkish migrants from Bulgaria in 1989, the Turkish state has proceeded to enact a series of visa regime changes concerning more recent migrants from Bulgaria, who, according to the most recent ...
Kasli, Zeynep Ulker +3 more
core +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
EUROPEAN DIPLOMATIC ACTION IN THE CONTEXT OF NOVEL CHALLENGES RELATED TO GLOBAL CLIMATE MIGRATIONS [PDF]
EURINT, 2019 Civil wars in Darfur or Syria showed what the global effects of migration could be and proved the importance of creation of multi-stakeholder partnerships.
Monica RADU, Dorin DUSCIAC
doaj