Results 41 to 50 of about 5,089,023 (378)
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
Measuring irregular migration in Chile: The use of data linkage methods
Foreign population in Chile almost doubled between 2017 and 2021. In recent years, the sources to measure the phenomenon has been the 2017 Census, plus administrative data from the migratory institutions.
Belén Harnecker, Felipe Mallea
doaj +1 more source
Planet migration: self-gravitating radiation hydrodynamical models of protoplanets with surfaces [PDF]
We calculate radial migration rates of protoplanets in laminar minimum mass solar nebula discs using three-dimensional self-gravitating radiation hydrodynamical (RHD) models.
Alexander +74 more
core +1 more source
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source
Forced labour and migration to the UK [PDF]
No description ...
Anderson, Bridget, Rogaly, Ben
core +1 more source
Transplantation stimulates interstitial cell migration in hydra [PDF]
Migration of interstitial cells and nerve cell precursors was analyzed in Hydra magnipapillata and Hydra vulgaris (formerly Hydra attenuata). Axial grafts were made between [3H]thymidine-labeled donor and unlabeled host tissue. Migration of labeled cells
Bosch +10 more
core +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Intensification of work-place regimes in British agriculture: the role of migrant workers [PDF]
In Britain, international migrants have very recently become the major workforce in labour-intensive agriculture. This paper explores the causes of the dramatic increase since the 1990s in the employment of migrant workers in this sub-sector.
Rogaly, Ben
core
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Cell scratch test and Transwell were used to measure the migration abilities of HSVSMCs. NC = Negative control group, only control siRNA transfected; GAS5(-) = lncRNA-GAS5 knockdown group transfected with silence siRNA.
Erlinda The (605317) +13 more
core +4 more sources

