Results 51 to 60 of about 2,950,715 (249)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Migrant arrivals and deaths in the Mediterranean: what do the data really tell us?
Forced Migration Review, 2016 The policy and media gaze focuses on numbers of migrant arrivals and deaths. There are problems in the data for both categories.
Frank Laczko +3 more
doaj
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Environmental Change and Migration: Governmental Compensation Policies to Natural Disasters Victims and Urbanization Process: A Case Study of Wildfires in Russian Federation in 2010 [PDF]
, 2011 Bobylev N. Environmental Change and Migration: Governmental Compensation Policies to Natural Disasters Victims and Urbanization Process: A Case Study of Wildfires in Russian Federation in 2010. COMCAD Arbeitspapiere - Working Papers, 100.
Bobylev, Nikolai
core
An Overview of Anthropological Regional Studies
International Journal of Anthropology and Ethnology, 2019 Regional studies in anthropology are vital to the development of the discipline, for they supply anthropology with an approach that moves from individual cases to a holistic understanding of a region. Western anthropologists’ interests in researching non-
Daming Zhou +3 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Social Mechanisms Underlying Network Effects in Mexico-U.S. Migration
, 2017 Scholars have long noted how migration streams, once initiated, obtain a self-feeding character. Studies have attributed this phenomenon, called the cumulative causation of migration, to expanding social networks that connect migrants in destination to ...
Filiz Garip, Asad, Asad Lugman
core +6 more sources
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
India Migration Report 2024: Indians in Canada is one of the first volumes to comprehensively examine and analyse the different facets of Indian migration to Canada.
core +1 more source