Results 71 to 80 of about 2,950,715 (249)

The discourse and practices of Polish migration policy during the COVID-19 pandemic – economisation as a form of emergency governance

open access: yesComparative Migration Studies
The existing literature points to securitisation as a dominant form of emergency governance emerging in response to the COVID-19 pandemic, also in relation to migration.
Marta Jaroszewicz   +2 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Migration and Health: a fast Changing European Scenario

open access: yesEl Guiniguada, 2016
La migración está cambiando el desarrollo económico y demográfico de la Unión Europea y de los países de la Asociación del Mercado Libre Europeo y, desde la perspectiva de la salud, está afectando a la epidemiología de la enfermedad.
Manuel Carballo   +2 more
doaj  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

South-South migration and human development: Reflections on African experiences [PDF]

open access: yes, 2009
This paper looks at the relationship between migration between developing countries – or countries of the global ‘South’ – and processes of human development.
Bakewell, Oliver; id_orcid   +1 more
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Addressing internal displacement in Ethiopia

open access: yesForced Migration Review, 2018
Among various new initiatives in Ethiopia to address both the short- and long-term needs of IDPs, the Durable Solutions Working Group is making some progress, despite the challenging context.
Behigu Habte, Yun Jin Kweon
doaj  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Systematic review of empiric studies on lockdowns, workplace closures, and other non-pharmaceutical interventions in non-healthcare workplaces during the initial year of the COVID-19 pandemic: benefits and selected unintended consequences

open access: yesBMC Public Health
Background We conducted a systematic review aimed to evaluate the effects of non-pharmaceutical interventions within non-healthcare workplaces and community-level workplace closures and lockdowns on COVID-19 morbidity and mortality, selected mental ...
Faruque Ahmed   +6 more
doaj   +1 more source

„Chłop polski w Europie i Ameryce” jako (nadal) źródło inspiracji dla badan biograficznych i społecznego doświadczenia migracji

open access: yesPrzegląd Socjologiczny, 2019
Thomas i Znaniecki pokazali nam, jak za pomocą dokumentów osobistych badać relacje między jednostkami i „ich” społeczeństwem. To inspirujące podejście pozwoliło na podmiotowe traktowanie migrantów, co oznaczało zmianę perspektywy badawczej.
Catherine Delcroix
doaj   +1 more source

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