Results 81 to 90 of about 2,228,529 (317)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

When migration is not migration

Journal of Vascular Surgery: Venous and Lymphatic Disorders, 2021
Mitchell D, Eggers, Steven Y, Huang, Joseph R, Steele   +2 more
openaire   +2 more sources

Migration transitions: a theoretical and empirical inquiry into the developmental drivers of international migration

, 2010
This paper aims to advance a conceptual framework on the developmental drivers of international migration processes and to provide an empirical test drawing on the global migrant origin database.
de Haas, Hein
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Health vulnerabilities of cross-border migrants in Nepal, a cross-sectional mix-method study

Safety and Health at Work, 2022
KC Radheshyam Krishna, Kolitha Prabhash Wickramage   +1 more
doaj   +1 more source

The discourse and practices of Polish migration policy during the COVID-19 pandemic – economisation as a form of emergency governance

Comparative Migration Studies
The existing literature points to securitisation as a dominant form of emergency governance emerging in response to the COVID-19 pandemic, also in relation to migration.
Marta Jaroszewicz, Mateusz Krępa, Marta Pachocka   +2 more
doaj   +1 more source

Labour Migration for Vulnerable Communities: A Strategy to Adapt to a Changing Environment

, 2011
de Moor N. Labour Migration for Vulnerable Communities: A Strategy to Adapt to a Changing Environment. COMCAD Arbeitspapiere - Working Papers, 101.
Moor, Nicole de, de Moor, Nicole
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Migration as an Adaptation Strategy and Its Consequences on Coastal Society: Experience from Bangladesh

, 2011
Mallick B. Migration as an Adaptation Strategy and Its Consequences on Coastal Society: Experience from Bangladesh. COMCAD Arbeitspapiere - Working Papers, 96.
Mallick, Bishawjit
core