Results 91 to 100 of about 2,228,529 (317)

Summary report on the MIPEX health strand and country reports [PDF]

, 2016
The Migrant Integration Policy Index (MIPEX) Health strand is a questionnaire designed to supplement the existing seven strands of the MIPEX, which in its latest edition (2015) monitors policies affecting migrant integration in 38 different countries ...
International Organization for Migration, Buttigieg, Sandra C.   +1 more
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Migration and Health: a fast Changing European Scenario

El Guiniguada, 2016
La migración está cambiando el desarrollo económico y demográfico de la Unión Europea y de los países de la Asociación del Mercado Libre Europeo y, desde la perspectiva de la salud, está afectando a la epidemiología de la enfermedad.
Manuel Carballo, Sofiat Akinola, Sebastián Carballo   +2 more
doaj  

The migration-remittances-development-nexus: ‘Mi casa con Remesas’ and transnational flows between Colombia and London

, 2011
Zapata GP. The migration-remittances-development-nexus: ‘Mi casa con Remesas’ and transnational flows between Colombia and London. COMCAD Arbeitspapiere - Working Papers, 106.
Zapata, Gisela P.
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Addressing internal displacement in Ethiopia

Forced Migration Review, 2018
Among various new initiatives in Ethiopia to address both the short- and long-term needs of IDPs, the Durable Solutions Working Group is making some progress, despite the challenging context.
Behigu Habte, Yun Jin Kweon
doaj  

Systematic review of empiric studies on lockdowns, workplace closures, and other non-pharmaceutical interventions in non-healthcare workplaces during the initial year of the COVID-19 pandemic: benefits and selected unintended consequences

BMC Public Health
Background We conducted a systematic review aimed to evaluate the effects of non-pharmaceutical interventions within non-healthcare workplaces and community-level workplace closures and lockdowns on COVID-19 morbidity and mortality, selected mental ...
Faruque Ahmed, Livvy Shafer, Pallavi Malla, Roderick Hopkins, Sarah Moreland, Nicole Zviedrite, Amra Uzicanin   +6 more
doaj   +1 more source

Unlocking migration politics: researching beyond biases and gaps in migration studies and comparative politics

, 2019
International audienceThe focus of research in contemporary international migration and integration politics has long been immigration to Western democracies and their related migration corridors, often defined by colonial history. Just like in any field
Thiollet, Hélène
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source