Results 91 to 100 of about 472,776 (289)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

From the migration crisis to the COVID-19 pandemic, (im)possible regularization of migrants in Italy and Spain. [PDF]

Int Migr, 2022
Aris Escarcena JP.
europepmc   +1 more source

Climate Change, Migration, and Conflict: Addressing Complex Crisis Scenarios in the 21st Century [PDF]

, 2012
Outlines how climate change, migration, and conflict intersect in Africa, Asia, and the Americas and implications for national, human, and environmental security.
Laura Conley, Michael Werz
core  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Analyzing the EU Migration Crisis as Reflected on Twitter. [PDF]

KN J Cartogr Geogr Inf, 2022
Mukherjee S, Hauthal E, Burghardt D.
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

New challenges for the modern migration policy of the European Union

Studia Humanitatis, 2015
The article analyses the migration policy of the European Union in the context of contemporary global development and the existing European migration crisis. The article explains factors and principles of migration policy.
Malykha Mariia Igorivna
doaj  

A Migration Crisis or the Crisis of the European Union?

Социологическая наука и социальная практика, 2019
Drawing on the works of Russian and foreign scholars and using my own experience of communication with the EU migrants in the run of my long-term stay in Europe, I came to the following conclusions.
Oleg N. Yanitsky
doaj   +1 more source

The Plasticity of Our Fears: Affective Politics in the European Migration Crisis. [PDF]

Society, 2021
Heins VM.
europepmc   +1 more source

Is the migration crisis a solidarity crisis? [PDF]

, 2017
This chapter aims to analyse to what extent and how increased migration to Europe has triggered conflicting ideas of solidarity in Europe. It integrates analytical and normative approaches to the concept of solidarity. The chapter analyses how appeals for solidarity are used to justify a certain policy.
openaire   +2 more sources