Results 31 to 40 of about 472,776 (289)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
, 2014 Crisis and migration have a long association, in popular and policy discourse as well as in social scientific analysis. Despite the emergence of more nuanced and even celebratory accounts of mobility in recent years, there remains a persistent emphasis on migration being either a symptom or a cause of crisis. Moreover, in the context of a recent series
openaire +1 more source
BALTIC TRIPLETS? OUT-MIGRATION MIGRATION AND RESPONSES TO CRISIS [PDF]
Regional Formation and Development Studies, 2021 This article addresses intersections of migration and economic development as one of the most topical contemporary challenges inthe Baltic states. It uses empirical approach to compare governmental responses to recent economic crisis starting in 2008.
openaire +2 more sources
No. 29: Zimbabwe’s Return Migrants – Before & After Challenges [PDF]
, 2014 Various countries in the developing world have implemented policies and incentives to encourage the participation of their respective diasporas in development. The ‘best case’ countries include the Philippines, India, Mexico, Bangladesh, Nigeria, Morocco,
Mandiyanike, David
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
The internal and external aspects of the migration crisis in Germany [PDF]
Научно-аналитический вестник Института Европы РАН, 2018 The Minister of Internal Affairs of Germany H. Seehofer prepared in early June 2018 the «Migration Masterplan», with provisions for coalition agreement on migration. Federal Chancellor A.
Belov Vladislav
doaj +1 more source
Migration processes in Ukraine: threats in the conditions of the Russian-Ukrainian war
Економіка, управління та адміністрування, 2023 The migration processes in Ukraine in the last decade, as well as the issue of the modern migration crisis that arose as a result of the Russian-Ukrainian war, were studied.
O.V. , A.Y.
doaj +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source