Results 51 to 60 of about 35,868 (219)
Zagrożenia cywilizacyjne powiązane z kryzysem migracyjnym na granicy Rzeczypospolitej Polskiej
CIVILIZATION THREATS RELATED TO THE MIGRATION CRISIS ON THE BORDER OF THE REPUBLIC OF POLAND The article is devoted to the analysis of civilization threats resulting from the migration crisis on the Polish-Belarusian border.
Patryk Chmielarz
doaj +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Adolescence, food crisis and migration
Adolescents who migrate because of food crises face distinct risks. Specific strategies are needed to prevent and respond to this phenomenon.
Janis Ridsdel
doaj
Statelessness remains a secondary topic in the debate on the migration crisis that has been raging across Europe since 2015, but it will certainly come to the fore in the near future.
Agata Szwed
doaj +1 more source
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
European Borders in Turbulent Times: The Case of the Central Mediterranean ‘Extended Borderland’
This article presents one of the most salient aspects of the migration crisis in the EU, namely the turbulent management of external borders, and analyzing it in the case of the central region of the Mediterranean Sea.
Artur Gruszczak
doaj +1 more source
Rethinking Vulnerability as a Radically Ethical Device: Ethical Vulnerability Analysis and the EU's "Migration Crisis". [PDF]
Da Lomba S, Vermeylen S.
europepmc +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
New challenges for the modern migration policy of the European Union
The article analyses the migration policy of the European Union in the context of contemporary global development and the existing European migration crisis. The article explains factors and principles of migration policy.
Malykha Mariia Igorivna
doaj

